N-1-环己烯-1-基-N-苄基乙酰胺合成路线 （共 11 条）
反应条件
1: benzyl azide With triphenylphosphine in xylene
T=20°C; 1 h;
2: cyclohexanone in xylene
T=150°C; 0.5 h; microwave irradiation;
3: acetyl chloride With pyridine in xylene
T=0 - 20°C;
参考文献
Cassidy, Michael P.; Oezdemir, Ayse Daut; Padwa, Albert
Organic Letters, 2005 , vol. 7, # 7 p. 1339 - 1342
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene
T=110°C; 5-endo cyclization; 3 h; sealed tube;
参考文献
Curran, Dennis P.; Guthrie, David B.; Geib, Steven J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8437 - 8445
反应条件
pyridine in benzene
1 h; Ambient temperature;
参考文献
Erzhanov, K. B.; Kayukova, L. A.; Umarova, Z. N.; Yakimovich, S. I.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, p. 2106 - 2111
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 11 p. 2378 - 2384
反应条件
2,2'-azo-bisisobutyronitrile; tris-(trimethylsilyl)silane in toluene
4 h; Heating;
参考文献
Tamura, Osamu; Matsukida, Hana; Toyao, Atsushi; Takeda, Yoshifumi; Ishibashi, Hiroyuki
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5537 - 5545
反应条件
N,N-diethylaniline in toluene
T=0 - 20°C;
参考文献
Clark, Andrew J.; Curran, Dennis P.; Geden, Joanna V.; James, Natalie; Wilson, Paul
Journal of Organic Chemistry, 2011 , vol. 76, # 11 p. 4546 - 4551
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene
T=110°C; 5-endo cyclization; 3 h; sealed tubeInert atmosphere; ReactivityKinetics;
参考文献
Curran, Dennis P.; Guthrie, David B.; Geib, Steven J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8437 - 8445
反应条件
pyridine; 2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene
5-endo cyclization; 3 h; Syringe pumpReflux;
参考文献
Curran, Dennis P.; Guthrie, David B.; Geib, Steven J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8437 - 8445
反应条件
1: toluene / 2 h / Heating
2: 1.22 g / triethylamine / toluene / 4 h / 0 °C
3: 76 percent / (TMS)3SiH; AIBN / toluene / 4 h / Heating
View Scheme
参考文献
Tamura, Osamu; Matsukida, Hana; Toyao, Atsushi; Takeda, Yoshifumi; Ishibashi, Hiroyuki
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5537 - 5545
反应条件
1: toluene / 2 h / Heating
2: 1.22 g / triethylamine / toluene / 4 h / 0 °C
3: 76 percent / (TMS)3SiH; AIBN / toluene / 4 h / Heating
View Scheme
参考文献
Tamura, Osamu; Matsukida, Hana; Toyao, Atsushi; Takeda, Yoshifumi; Ishibashi, Hiroyuki
Journal of Organic Chemistry, 2002 , vol. 67, # 16 p. 5537 - 5545
反应条件
camphor-10-sulfonic acid; tetra-(n-butyl)ammonium iodide
2 h; Reactivity;
参考文献
Curran, Dennis P.; Guthrie, David B.; Geib, Steven J.
Journal of the American Chemical Society, 2008 , vol. 130, # 26 p. 8437 - 8445
