2,3-二甲氧基苯甲醛合成路线 （共 174 条）
反应条件
nitric acid in acetic acid
0.75 h; Ambient temperature;
参考文献
Fukuyama, Yoshiyasu; Iwatsuki, Chie; Kodama, Mitsuaki; Ochi, Masamitsu; Kataoka, Kumi; Shibata, Kozo
Tetrahedron, 1998 , vol. 54, # 34 p. 10007 - 10016
参考文献
Perkin; Robinson
Journal of the Chemical Society, 1914 , vol. 105, p. 2384
Full Text Show Details
Perkin; Robinson; Stoyle
Journal of the Chemical Society, 1924 , vol. 125, p. 1357
参考文献
Davies
Journal of the Chemical Society, 1923 , vol. 123, p. 1584
反应条件
1: sodium; ethyl acetate; ethanol
2: copper oxide-chromium oxide / 146 °C / 132391 Torr / Hydrogenation
View Scheme
参考文献
Mason
Journal of the American Chemical Society, 1947 , vol. 69, p. 2241
反应条件
1: NaH, Me2SO / tetrahydrofuran / 5 h / 5 °C
2: 57.6 g / H2 / 5percent Pd/C / acetic acid
View Scheme
参考文献
Bonner, Lisa A.; Laban, Uros; Chemel, Benjamin R.; Juncosa, Jose I.; Lill, Markus A.; Watts, Val J.; Nichols, David E.
ChemMedChem, 2011 , vol. 6, # 6 p. 1024 - 1040
反应条件
1: diethyl ether / 2 h / Heating
2: Na2Cr2O7; aq. H2SO4 / acetone / 3 h / 20 °C
View Scheme
参考文献
Albrecht, Markus; Mirtschin, Sebastian; De Groot, Marita; Janser, Ingo; Runsink, Jan; Raabe, Gerhard; Kogej, Michael; Schalley, Christoph A.; Froehlich, Roland
Journal of the American Chemical Society, 2005 , vol. 127, # 29 p. 10371 - 10387
反应条件
1: 90 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 20 °C
2: 88 percent / H2 / Pd/C / acetic acid / 1292.87 Torr
3: 65 percent / polyphosphoric acid / 40 h / 40 °C
View Scheme
参考文献
BAYLOR UNIVERSITY
Patent: US2012/130129 A1, 2012 ;
反应条件
(i) KOtBu, tBuOH, (ii) H2, Pd-C, EtOH, (iii) PCl5, SnCl4, benzene; Multistep reaction;
参考文献
Itoh; Sugihara; Miyake; Tada; Oka
Chemical and Pharmaceutical Bulletin, 1978 , vol. 26, # 2 p. 504 - 513
反应条件
sodium tetrahydroborate; thionyl chloride
1.) MeOH, RT; 2.) pyridine, RT;; Yield given. Multistep reaction;
参考文献
Ahmad; Snieckus
Canadian Journal of Chemistry, 1982 , vol. 60, # 21 p. 2678 - 2686
反应条件
piperidine; benzoic acid in toluene
4 h; Heating;
参考文献
Sohda; Mizuno; Hirata; Maki; Kawamatsu
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 2 p. 560 - 569
