potassium carbonate in N,N-dimethyl acetamide T=170°C; 3 h; Inert atmosphere;

diisobutylaluminium hydride in tetrahydrofuran; n-heptane; water; ethyl acetate; toluene

copper; 2,4-dichloro-phenol T=110°C; 48 h;

T=220°C; 2 h;

piperidine; pyridine 5 h; Heating;

sodium borohydride; sodium hydrogencarbonate in n-heptane; ethyl acetate; isopropyl alcohol

sodium tetrahydroborate in ethanol 16 h; Ambient temperature;

1: sodium borohydride / ethanol / 16 h / Ambient temperature 2: pyridine, thionyl chloride / benzene / 16 h / Heating 3: H2O; ethanol / 24 h / Heating 4: concd. HCl, acetic acid / 24 h / Heating View Scheme

1: sodium borohydride / ethanol / 16 h / Ambient temperature 2: pyridine, thionyl chloride / benzene / 16 h / Heating 3: H2O; ethanol / 24 h / Heating 4: concd. HCl, acetic acid / 24 h / Heating 5: thionyl chloride / 2 h / 100 °C 6: diethyl ether / Ambient temperature 7: AgNO3, NH4OH / dioxane / 16 h / Heating 8: aq. NaOH / 2-ethoxy-ethanol / 16 h / Heating View Scheme

tert.-butylhydroperoxide; Rhodium trichloride; triphenylphosphine in chlorobenzene T=160°C; 24 h; Inert atmosphere;