potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in DMF (N,N-dimethyl-formamide) T=80°C; 24 h;

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.75 h / -78 - 0 °C 1.2: -78 - 20 °C 2.1: potassium acetate / 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 80 °C / Inert atmosphere; Sealed tube View Scheme

1: sodium hexamethyldisilazane / tetrahydrofuran / 8 h / -78 °C / Inert atmosphere 2: potassium acetate / 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 90 °C / Inert atmosphere View Scheme

sodium periodate; ammonium acetate in water; acetone 48 h;