乙氧基甲叉丙二酸二乙酯合成路线 （共 444 条）
反应条件
1.1: 100 °C 1.2: PPA 2.1: POCl3 / Heating View Scheme
参考文献
Zask; Gu; Albright; Du; Hogan; Levin; Chen; Killar; Sung; DiJoseph; Sharr; Roth; Skala; Jin; Cowling; Mohler; Barone; Black; March; Skotnicki
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 8 p. 1487 - 1490
反应条件
Gould-Jacob reaction; 0.0416667 h; Irradiation;
参考文献
Dave, Chaitanya G.; Joshipura, Hardik M.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 3 p. 650 - 652
参考文献
Mane; Li; Huang; Gupta; Nadkarni; Giridhar; Naik; Yadav
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6296 - 6304
反应条件
1: 71 percent / benzene / 3.5 h / Heating 2: PPE / 2 h / 120 °C View Scheme
参考文献
Gall-Istok, K.; Sterk, L.; Deak, Gy.
Acta Chimica Hungarica, 1983 , vol. 112, # 2 p. 241 - 252
反应条件
1.1: benzene / 3.5 h / Reflux 2.1: polyphosphate ester(PPE) / methyloxirane / 2 h / 120 °C 2.2: pH 8 View Scheme
参考文献
GENZYME CORPORATION; TEICHER, Beverly A.; SCHMID, Steven M.
Patent: WO2012/15875 A1, 2012 ;
参考文献
Golub, Andriy G.; Yakovenko, Olexander Ya.; Bdzhola, Volodymyr G.; Sapelkin, Vladislav M.; Zien, Piotr; Yarmoluk, Sergiy M.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6443 - 6450
参考文献
ABBOTT LABORATORIES
Patent: WO2008/133753 A2, 2008 ;
Location in patent: Page/Page column 56 ;
反应条件
in toluene Substitution; Heating;
参考文献
Edmont, Dolores; Rocher, Richard; Plisson, Christophe; Chenault, Jacques
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 16 p. 1831 - 1834
参考文献
American Cyanamid Company
Patent: US6228869 B1, 2001 ;
US 6228869 B1
参考文献
Whitehead
Journal of the American Chemical Society, 1952 , vol. 74, p. 4267,4269
