肼基甲酸叔丁酯合成路线

870-46-2肼基甲酸叔丁酯

693287-79-52-(四氢吡喃-4-基)肼基甲酸叔丁酯

参考文献

PHARMASCIENCE, INC.; LAURENT, Alain; ROSE, Yannick; JAQUITH, James B.
Patent: WO2013/177668 A1, 2013 ;

29943-42-8四氢吡喃酮+

870-46-2肼基甲酸叔丁酯+

64-19-7醋酸

90271-04-82-甲基-2-丙基2-乙酰基肼羧酸酯+

693287-79-52-(四氢吡喃-4-基)肼基甲酸叔丁酯

参考文献

Verhoest, Patrick R.; Fonseca, Kari R.; Hou, Xinjun; Proulx-Lafrance, Caroline; Corman, Michael; Helal, Christopher J.; Claffey, Michelle M.; Tuttle, Jamison B.; Coffman, Karen J.; Liu, Shenpinq; Nelson, Frederick; Kleiman, Robin J.; Menniti, Frank S.; Schmidt, Christopher J.; Vanase-Frawley, Michelle; Liras, Spiros
Journal of Medicinal Chemistry, 2012 , vol. 55, # 21 p. 9045 - 9054

870-46-2肼基甲酸叔丁酯

92846-89-4

参考文献

Brosse, Nicolas; Pinto, Maria-Fatima; Jamart-Gregoire, Brigitte
European Journal of Organic Chemistry, 2003 , # 24 p. 4757 - 4764

870-46-2肼基甲酸叔丁酯

937046-96-32-氰基-1H-吡咯-1-氨基甲酸叔丁酯

参考文献

BIOCRYST PHARMACEUTICALS, INC.; BABU, Yarlagadda, S.; KOTIAN, Pravin, L.; CHINTAREDDY, Venkat, R.
Patent: WO2013/33093 A1, 2013 ;

870-46-2肼基甲酸叔丁酯+

76-83-5三苯基氯甲烷

97013-32-6

参考文献

Carpino,L.A. et al.
Journal of Organic Chemistry, 1961 , vol. 26, p. 4336 - 4340

870-46-2肼基甲酸叔丁酯

99768-83-9乙酰氧基氨基甲酸叔丁酯

参考文献

Carpino et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 955

870-46-2肼基甲酸叔丁酯

476362-41-12-甲基-2-丙基2-乙基肼羧酸酯

参考文献

SOVA PHARMACEUTICALS, INC.; DURON, Sergio, G.; CHAPMAN, Justin; SYDSERFF, Simon, G.; RAO, Srinivas, G.; STEIN, Gregory; WADE, Warren
Patent: WO2014/18570 A1, 2014 ;

870-46-2肼基甲酸叔丁酯+

75-07-0乙醛

56572-28-22-甲基-2-丙基(2E)-2-亚乙基肼羧酸酯

参考文献

Bredihhin, Aleksei; Maeeorg, Uno
Tetrahedron, 2008 , vol. 64, # 28 p. 6788 - 6793

870-46-2肼基甲酸叔丁酯+

1142-20-7N-苄氧羰基-L-丙氨酸

5721-18-62-[(S)-1-氧代-2-[[(苄氧基)羰基]氨基]丙基]肼-1-羧酸叔丁酯

参考文献

Yanaihara; Sakagami; Nakajima; Nakayama
Chemical and pharmaceutical bulletin, 1973 , vol. 21, # 3 p. 616 - 621

870-46-2肼基甲酸叔丁酯+

78-84-2异丁醛

57699-53-3

参考文献

Sund, Christian; Belda, Oscar; Borkakoti, Neera; Lindberg, Jimmy; Derbyshire, Dean; Vrang, Lotta; Hamelink, Elizabeth; Hgren, Cathrine; Woestenenk, Esmeralda; Wikstroem, Kristina; Eneroth, Anders; Lindstroem, Erik; Kalayanov, Genadiy
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6721 - 6727,7