1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
1: (i) nBuLi, THF, hexane, (ii) /BRN= 1420778/ 2: Li, EtNH2 / -78 °C View Scheme
参考文献
Nederlof,P.J.R. et al.
Tetrahedron, 1977 , vol. 33, p. 579 - 580
反应条件
1: n-BuLi / tetrahydrofuran 2: Na-Hg 3: HgCl2 4: 2) H3O(+) View Scheme
参考文献
Isobe, Minoru; Obeyama, Junko; Funabashi, Yasunori; Goto, Toshio
Tetrahedron Letters, 1988 , vol. 29, # 37 p. 4773 - 4776
反应条件
in tetrahydrofuran T=25°C; 20 h;
参考文献
Journal of Fluorine Chemistry, , vol. 44, p. 275 - 284
反应条件
1: 74 percent / K2CO3 / acetone / 1 h / Heating 2: 86 percent / 3-chloroperoxybenzoic acid / CH2Cl2 / 3.5 h / -10 - 20 °C 3: 92 percent / aq. perchloric acid / dioxane / 1 h / 20 °C View Scheme
参考文献
Row; Brown; Stachulski; Lennard
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 8 p. 1604 - 1610
反应条件
1: 4-6-dibromoresorcinal dimethyl ether With n-butyllithium 2: prenyl bromide
参考文献
Pahari, Pallab; Rohr, Juergen
Journal of Organic Chemistry, 2009 , vol. 74, # 7 p. 2750 - 2754
反应条件
1: diethyl ether 2: nickel / aluminium oxide / 160 - 170 °C / Hydrogenation View Scheme
参考文献
Lewina et al.
Vestnik Moskovskogo Universiteta, 1957 , vol. 12, # 3 p. 165,167,168
Chem.Abstr., 1958 , p. 6141
反应条件
1.1: sodium hydride / tetrahydrofuran / 1 h / 0 - 23 °C / |Inert atmosphere 1.2: 16 h / 23 °C / |Inert atmosphere 2.1: Ru(Cp)(PPh2PytBu)2(MeCN)PF6; (Ru2(η5-C5Ph4O)2(H)2(CO)4); water / isopropyl alcohol / 3 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Li, Le; Herzon, Seth B.
Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17376 - 17379,4
Title/Abstract Full Text Show Details
Li, Le; Herzon, Seth B.
Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17376 - 17379
反应条件
1: 4-hydroxybutanol With sodium hydride in N,N-dimethyl-formamide; mineral oil 0.75 h; 2: prenyl bromide in N,N-dimethyl-formamide; mineral oil
参考文献
Comito, Robert J.; Finelli, Fernanda G.; Macmillan, David W. C.
Journal of the American Chemical Society, 2013 , vol. 135, # 25 p. 9358 - 9361
反应条件
1: n-butyllithium / tetrahydrofuran / -45 °C 2: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether View Scheme
参考文献
Bondalapati, Somasekhar; Indukuri, Kiran; Ghosh, Priya; Saikia, Anil K.
European Journal of Organic Chemistry, 2013 , # 5 p. 952 - 956
反应条件
ammonium chloride; zinc in tetrahydrofuran; water appropriate alkyltin chloride is added to THF/H2O mixt. with excess of zinc powder, appropriate allyl bromide is added dropwise under stirring within 5 min, mixt. is stirred for 30 min; extn. (petroleum ether), separated org. layer is washed (aq. NaCl), drying (MgSO4), solvent is removed, distn., mixt. of isomers 3-methyl-1-buten-3-yltributyltin and 2-methyl-2-butenyltributyltin ratio 40:60; total yield 62percent;
参考文献
Gyldenfeldt, Friederike von; Marton, Daniele; Tagliavini, Giuseppe
Organometallics, 1994 , vol. 13, p. 906 - 913
