1-溴-3-甲基-2-丁烯合成路线 （共 689 条）
反应条件
ammonium hydrogen carbonate in water; acetone
T=20°C; 2 h;
参考文献
Westermaier, Martin; Mayr, Herbert
Organic Letters, 2006 , vol. 8, # 21 p. 4791 - 4794
反应条件
zinc in tetrahydrofuran
T=20°C; Barbier reaction; 4 h;
参考文献
Yadav; Reddy; Reddy, P.Muralikrishna; Srinivas
Tetrahedron Letters, 2002 , vol. 43, # 29 p. 5185 - 5187
反应条件
ammonium hydrogen carbonate in water; acetone
T=20°C; 1 h;
参考文献
Westermaier, Martin; Mayr, Herbert
Organic Letters, 2006 , vol. 8, # 21 p. 4791 - 4794
反应条件
methylmagnesium bromide
1.) Et2O, benzene, 0 deg C, 30 min, 2.) 2.5 h; Yield given. Multistep reaction. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Wenkert, Ernest; Angell, E. Charles; Ferreira, Vitor F.; Michelotti, Enrique L.; Piettre, Serge R.; et al.
Journal of Organic Chemistry, 1986 , vol. 51, # 12 p. 2343 - 2351
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Amat, Mercedes; Hadida, Sabine; Sathyanarayana, Swargam; Bosch, Joan
Journal of Organic Chemistry, 1994 , vol. 59, # 1 p. 10 - 11
反应条件
1: 66 percent / KOH / dimethylsulfoxide / 1 h / Ambient temperature
2: 53 percent / phosphoryl chloride / 1 h / 35 °C
View Scheme
参考文献
Shinde, Anand H.; Vidyacharan, Shinde; Sharada, Duddu S.
Tetrahedron Letters, 2014 , vol. 55, # 19 p. 3064 - 3069
反应条件
1: [14C]-3-Methylindole; prenyl bromide
2: N,N-dimethyl-formamide With trichlorophosphate
Vilsmeier-Haack reaction; Further stages.;
参考文献
Prajapati, Dipak; Gadhwal, Sunil
Tetrahedron, 2004 , vol. 60, # 22 p. 4909 - 4913
反应条件
1: 2-methyl-4-hydroxy-1-butene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in diethyl ether; hexane
T=20°C; 6 h;
2: prenyl bromide in diethyl ether
T=-78 - 20°C; Further stages.;
参考文献
Yong, Kelvin H.; Lotoski, John A.; Chong, J. Michael
Journal of Organic Chemistry, 2001 , vol. 66, # 24 p. 8248 - 8251
反应条件
1: 1) Na / 1) benzene, reflux, 4 h, 2) a) 0 deg C, 5 h, b) overnight
2: Ambient temperature; oxidation on air
View Scheme
参考文献
De Bernardi; Vidari; Vita Finzi; Fronza
Tetrahedron, 1992 , vol. 48, # 35 p. 7331 - 7344
反应条件
sodium in diethyl ether
Heating;
参考文献
Mehta, Goverdhan; Pan, Subhas Chandra
Organic Letters, 2004 , vol. 6, # 5 p. 811 - 813
