N-叔丁基-2-甲氧基苯甲酰胺合成路线 （共 12 条）
反应条件
sulfuric acid in acetic acid
T=20°C; Ritter reaction; Inert atmosphereEnzymatic reaction;
参考文献
Milne, Jacqueline E.; Baum, Jean C.
Organic Syntheses, 2012 , vol. 89, p. 519 - 526
反应条件
palladium diacetate; triethylamine; triphenylphosphine in N,N-dimethyl-formamide
T=50°C; P=750.075 Torr; 91 h; Autoclave;
参考文献
Takacs, Attila; Abreu, Artur R.; Peixoto, Andreia F.; Pereira, Mariette; Kollar, Laszlo
Synthetic Communications, 2009 , vol. 39, # 9 p. 1534 - 1548
反应条件
palladium diacetate; triethylamine; triphenylphosphine in N,N-dimethyl-formamide
T=50°C; P=30003 Torr; 24 h; Autoclave;
参考文献
Takacs, Attila; Abreu, Artur R.; Peixoto, Andreia F.; Pereira, Mariette; Kollar, Laszlo
Synthetic Communications, 2009 , vol. 39, # 9 p. 1534 - 1548
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane
参考文献
Saito, Fumiyo; Kuramochi, Kouji; Nakazaki, Atsuo; Mizushina, Yoshiyuki; Sugawara, Fumio; Kobayashi, Susumu
European Journal of Organic Chemistry, 2006 , # 21 p. 4796 - 4799
反应条件
silver trifluoromethanesulfonate; acetic acid in 1,2-dichloro-ethane
T=20 - 70°C; 6 h; Inert atmosphere; chemoselective reaction;
参考文献
Xing, Dong; Xu, Xinfang; Yang, Liping
Synthesis, 2009 , # 20 p. 3399 - 3404
反应条件
sodium perchlorate in acetonitrile
1.), 0 deg C, 2.) 1 h, r.t.;
参考文献
Masui, Masaichiro; Ueshima, Takahiro; Yamazaki, Tomoko; Ozaki, Shigeko
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 6 p. 2130 - 2133
反应条件
1: SOCl2, DMF / CHCl3 / Heating
2: CH2Cl2 / 18 h / Ambient temperature
View Scheme
参考文献
Cipollina, Joseph A.; Ruediger, Edward H.; New, James S.; Wire, Mary E.; Shepherd, Timothy A.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 11 p. 3316 - 3328
反应条件
sodium perchlorate in acetonitrile
1.), 0 deg C, 2.) 1 h, r.t.;
参考文献
Masui, Masaichiro; Ueshima, Takahiro; Yamazaki, Tomoko; Ozaki, Shigeko
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 6 p. 2130 - 2133
反应条件
in dichloromethane
18 h; Ambient temperature;
参考文献
Cipollina, Joseph A.; Ruediger, Edward H.; New, James S.; Wire, Mary E.; Shepherd, Timothy A.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 11 p. 3316 - 3328
反应条件
1: 45 percent / sodium carbonate / CHCl3 / 1.) 1 h, 0 deg C, 2.) 1 h, r.t.
2: 54 percent / 0.1 M NaClO4 / acetonitrile / 1.), 0 deg C, 2.) 1 h, r.t.
View Scheme
参考文献
Masui, Masaichiro; Ueshima, Takahiro; Yamazaki, Tomoko; Ozaki, Shigeko
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 6 p. 2130 - 2133
