4-(2-噻吩)-2-吡咯烷酮合成路线 (共 5 条)
反应条件
hydrogenchloride in methanol; ethyl acetate
参考文献
Abbott Laboratories
Patent: US5086074 A1, 1992 ;
US 5086074 A
反应条件
hydrogen; nickel in ethanol
P=760 Torr; Ambient temperature; Title compound not separated from byproducts;
参考文献
Berthelot; Vaccher; Flouquet; Debaert; Luyckx; Brunet
Journal of Medicinal Chemistry, 1991 , vol. 34, # 8 p. 2557 - 2560
反应条件
1: trimethylbenzyl ammonium hydroxide
2: hydrogen / Raney nickel
View Scheme
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
反应条件
hydrogen; nickel
Yield given;
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358