1-苯基-1H-苯并三唑合成路线 （共 27 条）
反应条件
1.1: sodium nitrite; hydrogenchloride / water / 0.17 h / 0 °C
1.2: -25 °C
2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 0 °C
3.1: potassium permanganate / acetone / 15 h
4.1: acetonitrile / 0.25 h / |Photolysis
View Scheme
参考文献
Gann, Adam W.; Amoroso, Jon W.; Einck, Vincent J.; Rice, Walter P.; Chambers, James J.; Schnarr, Nathan A.
Organic Letters, 2014 , vol. 16, # 7 p. 2003 - 2005
反应条件
tert.-butylnitrite in acetonitrile
Reflux;
参考文献
Zhang, Fengzhi; Moses, John E.
Organic Letters, 2009 , vol. 11, # 7 p. 1587 - 1590
反应条件
in acetonitrile
0.25 h; Photolysis;
参考文献
Gann, Adam W.; Amoroso, Jon W.; Einck, Vincent J.; Rice, Walter P.; Chambers, James J.; Schnarr, Nathan A.
Organic Letters, 2014 , vol. 16, # 7 p. 2003 - 2005
反应条件
copper(I) oxide; 1,10-phenanthroline; tetrabutyl ammonium fluoride
T=140 - 145°C; 48 h;
参考文献
Tang, Bo-Xiao; Guo, Sheng-Mei; Zhang, Man-Bo; Li, Jin-Heng
Synthesis, 2008 , # 11 p. 1707 - 1716
反应条件
sodium hydroxide; Cu(II) phenylcyclopropyl carboxylate; palladium diacetate; (tppts)2 in water
T=100°C; 6 h; withou Cu salt, without Pd catalyst; Product distribution;
参考文献
Beletskaya, Irina P.; Davydov, Dmitri V.; Moreno-Manas, Marcial
Tetrahedron Letters, 1998 , vol. 39, # 31 p. 5621 - 5622
反应条件
1: Et3N / benzene / 1 h / 0 - 5 °C
2: 67 percent / Et3N / CH2Cl2 / 1 h / 0 - 5 °C
View Scheme
参考文献
Singh, Neera; Dureja, Prem
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1997 , vol. 36, # 8 p. 700 - 702
反应条件
1.1: hydrogenchloride / acetonitrile / 0.25 h / -10 - 20 °C
1.2: 0.5 h / Cooling
1.3: 0.5 h / -10 - 20 °C
2.1: 1,3-bis-(diphenylphosphino)propane; potassium acetate; palladium diacetate / N,N-dimethyl-formamide / 12 h / 110 °C / Inert atmosphere; Sealed tube
View Scheme
参考文献
Zhou, Jun; He, Jianjun; Wang, Binjie; Yang, Weijun; Ren, Hongjun
Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 6868 - 6870
