(2-氧代-2-哌啶-1-基-乙基)-氨基甲酸叔丁酯合成路线 (共 5 条)
反应条件
hydrogenchloride in ethyl acetate Ambient temperature;
参考文献
Venuti, Michael C.; Alvarez, Robert; Bruno, John J.; Strosberg, Arthur M.; Gu, Leo; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2145 - 2152
反应条件
dicyclohexyl-carbodiimide in ethyl acetate
参考文献
Venuti, Michael C.; Alvarez, Robert; Bruno, John J.; Strosberg, Arthur M.; Gu, Leo; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2145 - 2152
反应条件
1: 1-(4-carboxyphenyl)-3-(4-nitrophenyl)-2-pyrazolin-5-one; amino polystyrene With dacarbazine; 4-(N,N-dimethlyamino)pyridine in N,N-dimethyl-formamide
24 h;
2: BOC-glycine With dacarbazine; 4-(N,N-dimethlyamino)pyridine in N,N-dimethyl-formamide
24 h;
3: piperidine in tetrahydrofuran; dichloromethane
T=20°C; 1 h;
参考文献
Byun, Jang-Woong; Lee, Dong-Hoon; Lee, Yoon-Sik
Tetrahedron Letters, 2003 , vol. 44, # 44 p. 8063 - 8067
反应条件
in N,N-dimethyl-formamide
T=20°C; Kinetics;
参考文献
Raz, Richard; Rademann, Joerg
Organic Letters, 2011 , vol. 13, # 7 p. 1606 - 1609
反应条件
Lawesson's reagent in benzene
T=80°C;
参考文献
Clausen, Kim; Thorsen, Michael; Lawesson, Sven-Olov; Spatola, Arno F.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 785 - 798