4-甲基-2-硝基苯胺合成路线 （共 173 条）
参考文献
Pande, Anil; Lokhande, S. R.; Patel, Madhuben R.; Khadse, B. G.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 3 p. 311 - 312
反应条件
1: Raney Ni, H2 / ethanol 2: ethanol View Scheme
参考文献
El'tsov; Selitrenikov; Rtishchev
Russian Journal of General Chemistry, 1997 , vol. 67, # 2 p. 285 - 294
反应条件
1: 70 percent 2: 87 percent / iron; acetic acid / ethanol View Scheme
参考文献
Chandler, Stephen A.
Journal of the Chemical Society, Perkin Transactions 2, 2001 , # 2 p. 214 - 228
反应条件
1.1: 29 percent / N-chlorosuccinimide / acetonitrile / Heating 2.1: sulfuric acid; aq. sodium nitrite / ethanol / 0.5 h / 0 - 20 °C 2.2: 69 percent / ethanol; H2O / Heating 3.1: 93 percent / tin(II) chloride dihydrate / ethanol / 3 h / Heating View Scheme
参考文献
Kovacic,P.; Gormish,J.F.
Journal of the American Chemical Society, 1966 , vol. 88, # 16 p. 3819 - 3824
反应条件
iodine; silver nitrate in ethanol
T=20°C; 8 h;
参考文献
Kim, Soon Ha; Kim, Hyoung Jin; Chung, Chul Woong; Park, Heui Sul; Kwak, Hyo Shin; Kim, Sung Ho; Park, Jin Gu
Patent: US2010/291533 A1, 2010 ;
Location in patent: Page/Page column 21 ;
参考文献
Wheeler
American Chemical Journal, 1910 , vol. 44, p. 131
Chem. Zentralbl., 1910 , vol. 81, # II p. 877
反应条件
FeCl3·6H2O; sulfur in neat (no solvent)
T=120°C; 24 h; Inert atmosphere; Overall yield = 80 percent;
参考文献
Nguyen, Thanh Binh; Retailleau, Pascal; Al-Mourabit, Ali
Organic Letters, 2013 , vol. 15, # 20 p. 5238 - 5241
反应条件
tin(ll) chloride in ethanol; water
0.333333 h; Reflux;
参考文献
Shi, Da-Qing; Dou, Guo-Lan; Ni, Sai-Nan; Shi, Jing-Wen; Li, Xiao-Yue
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 6 p. 1797 - 1801
反应条件
1: 74 percent / Et3N / tetrahydrofuran / 8 h / 20 °C
2: 62 percent / H2; ammonium formate; Pd/C / ethanol / 0.67 h / 20 °C
3: 85 percent / LiAlH4 / tetrahydrofuran / 20 °C
View Scheme
参考文献
Legrand, Yves-Marie; Gray, Mark; Cooke, Graeme; Rotello, Vincent M.
Journal of the American Chemical Society, 2003 , vol. 125, # 51 p. 15789 - 15795
反应条件
1: 74 percent / Et3N / tetrahydrofuran / 8 h / 20 °C
2: 62 percent / H2; ammonium formate; Pd/C / ethanol / 0.67 h / 20 °C
View Scheme
参考文献
Legrand, Yves-Marie; Gray, Mark; Cooke, Graeme; Rotello, Vincent M.
Journal of the American Chemical Society, 2003 , vol. 125, # 51 p. 15789 - 15795
