1.1: 91 percent / Br2 / acetic acid / 4 h / 25 °C 2.1: 61 percent / TFA; TFAA / 10 h / 0 - 25 °C 3.1: K2CO3; KI; CuI / acetone / 1 h / Heating 3.2: 90 percent / acetone; dimethylformamide / 15 h / 150 °C View Scheme

thionyl chloride

1: alcoholic sodium ethylate 2: KOH View Scheme

diethyl ether; silver(l) oxide

sodium hydroxide

暂无反应条件数据

phosphorus trichoride in toluene 4 h; Heating;

1: sodium acetate 2: AlCl3 View Scheme

1.1: potassium carbonate / acetone / 24 h / |Reflux 2.1: sodium hydroxide; water / methanol / 12 h / |Reflux 3.1: 4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h / 20 °C 4.1: sodium hydride / tetrahydrofuran / 1 h / |Reflux 5.1: potassium carbonate / acetone / 0.17 h 5.2: 2 h / 50 °C 6.1: copper dichloride; chloro-trimethyl-silane / acetonitrile / 0.5 h / 20 °C 7.1: Lindlar's catalyst; ammonium formate / methanol; ethyl acetate / 0.67 h / 50 °C 8.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C 9.1: hydrogenchloride; water / tetrahydrofuran / 5 h / |Reflux 10.1: tetrakis(triphenylphosphine) palladium(0) / tetrahydrofuran / 0.17 h / 20 °C / |Inert atmosphere 11.1: sodium acetate / acetic anhydride / 6 h / 170 °C / |Microwave irradiation 11.2: 0.5 h / 20 °C View Scheme

pyridine; 4-(N,N-dimethlyamino)pyridine T=20°C; 24 h;