雄甾-1,4-二烯-3,17-二酮合成路线 （共 75 条）
反应条件
1.1: toluene / 2 h / |Reflux 1.2: 1 h 2.1: copper(l) chloride / ethanol / 2 h / 20 °C / |Inert atmosphere 2.2: 20 °C / |Inert atmosphere 2.3: 20 °C View Scheme
参考文献
Wang, Chunli; Chen, Xiaoyu; Huang, Yaoqing; Yang, Jesse; Chen, Ying
Steroids, 2013 , vol. 78, # 14 p. 1339 - 1346
反应条件
sodium hydroxide; hydrogen; palladium on activated charcoal in methanol Further byproducts.;
参考文献
Steroids, , vol. 72, # 6-7 p. 545 - 551
反应条件
1: dibenzoyl peroxide; CCl4; N-bromo-succinimide 2: 2,4,6-trimethyl-pyridine View Scheme
参考文献
Journal of the American Chemical Society, , vol. 72, p. 4531,4533
反应条件
sodium hydroxide; pentacarbonyliron(0) in methanol; water T=50 - 60°C; 16 h;
参考文献
Kuenzer, H.; Stahnke, M.; Sauer, G.; Wiechert, R.
Tetrahedron Letters, 1990 , vol. 31, # 27 p. 3859 - 3862
反应条件
hydrogen; Wilkinson's catalyst in benzene T=20°C; 2 h; Yield given;
参考文献
Goncharova, N. M.; Grinenko, G. S.
Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 4 p. 245 - 246
Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 4 p. 61 - 63
反应条件
sodium hydroxide; hydrogen; palladium on activated charcoal in methanol Further byproducts.;
参考文献
Steroids, , vol. 72, # 6-7 p. 545 - 551
反应条件
diethyl-1,4-dihydro-2,6-dimethyl-3,5-pyridine dicarboxylate; 5 palladium on charcoal in ethanol 22 h; Reflux; stereoselective reaction;
参考文献
Ramachary, Dhevalapally B.; Sakthidevi, Rajasekar; Reddy, P. Srinivasa
RSC Advances, 2013 , vol. 3, # 32 p. 13497 - 13506
反应条件
1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction 2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction View Scheme
参考文献
Verheyden; Noppe; Zorn; Van Immerseel; Bussche, J. Vanden; Wille; Bekaert; Janssen; De Brabander; Vanhaecke
Journal of Steroid Biochemistry and Molecular Biology, 2010 , vol. 119, # 3-5 p. 161 - 170
反应条件
T=25°C; 72 h; stereoselective reduction in the biotransformation by cell suspension cultures of Marchantia Polymorpha, other androsterone derivative;
参考文献
Verheyden; Noppe; Zorn; Van Immerseel; Bussche, J. Vanden; Wille; Bekaert; Janssen; De Brabander; Vanhaecke
Journal of Steroid Biochemistry and Molecular Biology, 2010 , vol. 119, # 3-5 p. 161 - 170
反应条件
1: 20 h / Heating 2: 1.10 g / benzene; ethanol; H2O / 5 h / 20 °C 3: 60 percent / conc. HCl / 24 h / 20 °C View Scheme
参考文献
Goelitzer; Bonnekessel; Jones; Palusczak; Hartmann
Pharmazie, 2006 , vol. 61, # 7 p. 575 - 581
