(S)-3,4-二羟基丁酸甲酯合成路线 （共 18 条）
反应条件
1: With sodium tetrahydroborate; dimethylsulfide borane complex in tetrahydrofuran cooling; 2: With toluene-4-sulfonic acid in tetrahydrofuran; methanol T=20°C; 0.5 h;
参考文献
Ikura, Masahiro; Nakatani, Shingo; Yamamoto, Shingo; Habashita, Hiromu; Sugiura, Tsuneyuki; Takahashi, Kanji; Ogawa, Koji; Ohno, Hiroyuki; Nakai, Hisao; Toda, Masaaki
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 12 p. 4241 - 4252
反应条件
1: With acetyl chloride 2: With sodium tetrahydroborate; dimethylsulfide borane complex in tetrahydrofuran T=23°C;
参考文献
Burnham Institute for Medical Research; The Texas A and M University System
Patent: US2009/124681 A1, 2009 ;
Location in patent: Page/Page column 11 ;
US 20090124681 A1
反应条件
hydrogen; Nishimura catalyst <(45.9percent Rh/19.9percent Pt) oxide> in methanol T=25°C; P=75007.5 Torr;
参考文献
Advanced Synthesis and Catalysis, , vol. 343, # 8 p. 802 - 808
反应条件
1: (-)-(S)-hydroxybutanedioic acid With thionyl chloride in methanol 2: dimethylsulfide borane complex With sodium tetrahydroborate in methanol
参考文献
Zeng, Xin; Yin, Biaolin; Hu, Zheng; Liao, Chenzhong; Liu, Jinglei; Li, Shang; Li, Zheng; Nicklaus, Marc C.; Zhou, Guangbiao; Jiang, Sheng
Organic Letters, 2010 , vol. 12, # 6 p. 1368 - 1371
反应条件
sodium tetrahydroborate in tetrahydrofuran; methanol; hexane; ethyl acetate
反应条件
sodium tetrahydroborate; dimethylsulfide borane in tetrahydrofuran T=23°C; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 17 p. 5285 - 5296
反应条件
dimethylsulfide borane complex Moriwaki's procedure;
参考文献
Tetrahedron: Asymmetry, , vol. 1, # 5 p. 307 - 310
参考文献
Journal of the Chemical Society, Chemical Communications, , # 6 p. 434 - 435
反应条件
toluene-4-sulfonic acid T=20°C; 48 h;
参考文献
Organic and biomolecular chemistry, , vol. 1, # 3 p. 552 - 559
反应条件
toluene-4-sulfonic acid T=20°C; 48 h;
参考文献
Organic and biomolecular chemistry, , vol. 1, # 3 p. 552 - 559
