3-(1-氨基乙基)-1-金刚烷醇盐酸盐合成路线 （共 6 条）
反应条件
ammonia; hydrogen; nickel in methanol T=100°C; P=71107.8 Torr; 6 h;
参考文献
Manchand; Cerruti; Martin; Hill; Merrett; Keech; Belshe; Connell; Sim
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 1992 - 1995
反应条件
sulfuric acid; nitric acid T=10 - 15°C;
参考文献
Lavrova, L. N.; Indulen, M. K.; Ryazantseva, G. M.; Korytnyi, V. S.; Yashunskii, V. G.
Pharmaceutical Chemistry Journal, 1990 , vol. 24, # 1 p. 35 - 39
Khimiko-Farmatsevticheskii Zhurnal, 1990 , vol. 24, # 1 p. 29 - 31
反应条件
2: 62 percent / liq. NH3, H2 / Raney Ni / methanol / 6 h / 100 °C / 71107.8 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 1992 - 1995
反应条件
trichloromonobromomethane; water; molybdenum hexacarbonate T=150°C; 6 h; Inert atmosphere; regioselective reaction;
参考文献
Khusnutdinov; Shchadneva; Mukhametshina; Dzhemilev
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 8 p. 1137 - 1142
反应条件
hydrogenchloride 48 h; Heating; Yield given;
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 1992 - 1995
反应条件
1: 91 percent / Br2 / 18 h / Heating 2: 2 N HCl / 48 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 7 p. 1992 - 1995
