(1-重氮-2-氧代-丙醇)-膦酸二甲酯合成路线

参考文献

Dickson, Hamilton D.; Smith, Stephon C.; Hinkle, Kevin W.
Tetrahedron Letters, 2004 , vol. 45, # 29 p. 5597 - 5599

162107-48-4(R)-2,2-二甲基-3-(n-boc)-4-乙炔噁唑啉+

173065-16-2(4S)-4-乙炔基-2,2-二甲基-1,3-噁唑烷-3-甲酸叔丁酯

参考文献

Temperini, Andrea; Capperucci, Antonella; Degl'Innocenti, Alessandro; Terlizzi, Raffaella; Tiecco, Marcello
Tetrahedron Letters, 2010 , vol. 51, # 31 p. 4121 - 4124

27421-51-81-甲基吲哚-2-甲醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

16498-68-31-(1-甲基-1H-吲哚-2-基)乙酮

参考文献

Baxendale, Ian R.; Ley, Steven V.; Mansfield, Andrew C.; Smith, Christopher D.
Angewandte Chemie, International Edition, 2009 , vol. 48, p. 4017 - 4021
Angewandte Chemie, 2009 , vol. 121, p. 4077 - 4081

112-54-9十二醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

26186-02-71-十三炔

参考文献

Roth, Gerald J.; Liepold, Bernd; Mueller, Stephan G.; Bestmann, Hans Juergen
Synthesis, 2004 , # 1 p. 59 - 62

1121-60-4吡啶-2-甲醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

1945-84-22-乙炔基吡啶

参考文献

F. HOFFMANN-LA ROCHE AG; GABRIEL, Stephen Deems; THOMAS, Andrew
Patent: WO2012/62623 A1, 2012 ;
Location in patent: Page/Page column 32 ;

110-42-9癸酸甲酯+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

2243-98-31-十一炔

参考文献

Dickson, Hamilton D.; Smith, Stephon C.; Hinkle, Kevin W.
Tetrahedron Letters, 2004 , vol. 45, # 29 p. 5597 - 5599

112-31-2正癸醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

2243-98-31-十一炔

参考文献

Ohira, Susumu
Synthetic Communications, 1989 , vol. 19, # 3and4 p. 561 - 564

500-22-13-吡啶甲醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

2510-23-83-乙炔基吡啶

参考文献

Kallander, Lara S.; Lu, Qing; Chen, Wenfang; Tomaszek, Thaddeus; Yang, Guang; Tew, David; Meek, Thomas D.; Hofmann, Glenn A.; Schulz-Pritchard, Christina K.; Smith, Ward W.; Janson, Cheryl A.; Ryan, M. Dominic; Zhang, Gui-Feng; Johanson, Kyung O.; Kirkpatrick, Robert B.; Ho, Thau F.; Fisher, Paul W.; Mattern, Michael R.; Johnson, Randall K.; Hansbury, Michael J.; Winkler, James D.; Ward, Keith W.; Veber, Daniel F.; Thompson, Scott K.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5644 - 5647

872-85-54-吡啶甲醛+

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯

2510-22-74-乙炔基吡啶

参考文献

Colombano, Giampiero; Travelli, Cristina; Galli, Ubaldina; Caldarelli, Antonio; Chini, Maria Giovanna; Canonico, Pier Luigi; Sorba, Giovanni; Bifulco, Giuseppe; Tron, Gian Cesare; Genazzani, Armando A.
Journal of Medicinal Chemistry, 2010 , vol. 53, # 2 p. 616 - 623

90965-06-3(1-重氮-2-氧代-丙醇)-膦酸二甲酯+

146553-06-2(R)-1-(甲氧基(甲基)氨基)-1-氧代-2-丙基氨基甲酸叔丁酯

118080-82-3(R)-(1-甲基-2-丙炔基)-氨基甲酸 1,1-二甲基乙酯

参考文献

Tetrahedron Letters, , vol. 45, # 29 p. 5597 - 5599