1,2,3,4-四氢异喹啉合成路线 （共 340 条）
反应条件
triethylamine in dichloromethane
参考文献
Aubert, Catherine; Huard-Perrio, Cecile; Lasne, Marie-Claire
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 19 p. 2837 - 2842
反应条件
in dichloromethane T=20°C; Acetylation; 1 h;
参考文献
Sugiura, Michiharu; Asai, Koosuke; Hatano, Keiichiro; Kurono, Yukihisa; Hamada, Yoshiki
Heterocycles, 2000 , vol. 53, # 4 p. 821 - 830
反应条件
in ethanol; water T=25°C; 72 h; by Cunninghamella echinulata;
参考文献
Holland, Herbert L.; Bergen, Eleanor J.; Chenchaiah, P. Chinna; Khan, Shaheer H.; Munoz, Benito; et al.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 502 - 507
反应条件
aluminium trichloride in dichloromethane T=90°C; 3 h;
参考文献
Bon, Eric; Bigg, Dennis C. H.; Bertrand, Guy
Journal of Organic Chemistry, 1994 , vol. 59, # 15 p. 4035 - 4036
反应条件
immobilization of Candida cylindracea lipase in hexane T=55°C; 14 h;
参考文献
Badgujar, Kirtikumar C.; Dhake, Kishor P.; Bhanage, Bhalchandra M.
Process Biochemistry, 2013 , vol. 48, # 9 p. 1335 - 1347
反应条件
ethyl (triphenylphosphoranylidene)acetate in dichloromethane T=20°C; 168 h;
参考文献
Desmaele, Didier
Tetrahedron Letters, 1996 , vol. 37, # 8 p. 1233 - 1236
反应条件
methyl (triphenylphosphoranylidene)acetate in dichloromethane 120 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 37, # 8 p. 1233 - 1236
反应条件
in methanol; dichloromethane 120 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 37, # 8 p. 1233 - 1236
反应条件
ethylmagnesium bromide 1.) THF, 70 deg C, 15 min, 2.) THF, 70 deg C, 2 min; Yield given. Multistep reaction;
参考文献
Aubert, Catherine; Huard-Perrio, Cecile; Lasne, Marie-Claire
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 19 p. 2837 - 2842
参考文献
Hoffmann-la Roche Inc.
Patent: US6339093 B1, 2002 ;
Location in patent: Example 8 ;
US 6339093 B1
