1,2,3,4-四氢异喹啉合成路线 （共 340 条）
反应条件
(+/-)-BINAP; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate in toluene
Buchwald-Hartwig reaction; Reflux;
参考文献
Buckley, Benjamin R.; Christie, Steven D. R.; Elsegood, Mark R. J.; Gillings, Claire M.; Page, Philip C. Bulman; Pardoe, William J. M.
Synlett, 2010 , # 6 p. 939 - 943
反应条件
potassium phosphate; copper(l) iodide in ethylene glycol; isopropyl alcohol
T=20 - 90°C; 24 h; Inert atmosphere;
参考文献
Hari, Durga Prasad; Koenig, Burkhard
Organic Letters, 2011 , vol. 13, # 15 p. 3852 - 3855
反应条件
copper diacetate in dichloromethane
12 h; Ambient temperature;
参考文献
Barton, Derek H. R.; Donnelly, Dervilla, M. X.; Finet, Jean-Pierre; Guiry, Patrick J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 9 p. 2095 - 2102
反应条件
sulfur in pyridine
6 h; Heating; Mechanism;
参考文献
Ajzert, Ilona K.; Takacs, Kalman
Liebigs Annalen der Chemie, 1987 , p. 1061 - 1064
反应条件
1: copper(l) iodide; potassium phosphate / isopropyl alcohol / 24 h / 90 °C / |Schlenk technique; |Inert atmosphere
2: C38H26N3OPt(1+)*ClO4(1-)*0.5H2O / N,N-dimethyl-formamide / 2 h / 20 °C / |Irradiation
View Scheme
参考文献
Zhong, Jian-Ji; Meng, Qing-Yuan; Wang, Ge-Xia; Liu, Qiang; Chen, Bin; Feng, Ke; Tung, Chen-Ho; Wu, Li-Zhu
Chemistry - A European Journal, 2013 , vol. 19, # 20 p. 6443 - 6450
反应条件
1: copper(l) iodide; potassium phosphate / isopropyl alcohol / 24 h / 90 °C / |Schlenk technique; |Inert atmosphere
2: C38H26N3OPt(1+)*ClO4(1-)*0.5H2O / acetonitrile / 2 h / 20 °C / |Irradiation
View Scheme
参考文献
Zhong, Jian-Ji; Meng, Qing-Yuan; Wang, Ge-Xia; Liu, Qiang; Chen, Bin; Feng, Ke; Tung, Chen-Ho; Wu, Li-Zhu
Chemistry - A European Journal, 2013 , vol. 19, # 20 p. 6443 - 6450
反应条件
1.1: 50 percent / KNO3; H2SO4 / 5 - 20 °C
2.1: 94 percent / Et3N / CH2Cl2 / 1 h / Heating
3.1: FeCl3*6H2O; activated carbon / methanol / 0.33 h / Heating
3.2: 85 percent / NH2NH2*H2O / methanol / 4 h / Heating
View Scheme
参考文献
Ajao, J. F.; Bird, C. W.
Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 329 - 331
反应条件
1.9 mol Au/HT; potassium tert-butylate in o-xylene
T=90°C; 24 h; Inert atmosphere;
参考文献
Zhu, Jiangling; Zhang, Yan; Shi, Feng; Deng, Youquan
Tetrahedron Letters, 2012 , vol. 53, # 25 p. 3178 - 3180
反应条件
[(DABCO)(AlMe3)2] in tetrahydrofuran
T=130°C; 0.2 h; microwave irradiation;
参考文献
Glynn, Daniel; Bernier, David; Woodward, Simon
Tetrahedron Letters, 2008 , vol. 49, # 39 p. 5687 - 5688
反应条件
triethylamine in dichloromethane
参考文献
Aubert, Catherine; Huard-Perrio, Cecile; Lasne, Marie-Claire
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 19 p. 2837 - 2842
