反应条件
1.1: 92 percent / bromine; acetic acid; KOAc / CH2Cl2 / 0.25 h
2.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C
2.2: trimethyl borate / tetrahydrofuran / 0.5 h / -78 °C
2.3: HCl / tetrahydrofuran; H2O
3.1: 95 percent / Na2CO3 / Pd(PPh3)4 / 1,2-dimethoxy-ethane; ethanol; H2O / 48 h / Heating
View Scheme
参考文献
Pathak, Rakhi; Nhlapo, Johanna M.; Govender, Sameshnee; Michael, Joseph P.; Van Otterlo, Willem A. L.; De Koning, Charles B.
Tetrahedron, 2006 , vol. 62, # 12 p. 2820 - 2830
