(S)-N-叔丁氧羰基-2-吡咯烷酮-5-甲酸叔丁酯合成路线 (共 24 条)
反应条件
4-(N,N-dimethlyamino)pyridine in acetonitrile 0.5 h;
参考文献
Tetrahedron Letters, , vol. 49, # 12 p. 1957 - 1960
反应条件
4-(N,N-dimethlyamino)pyridine in tert-butyl alcohol 12 h; RefluxInert atmosphere;
参考文献
Tetrahedron, , vol. 69, # 33 p. 6821 - 6825
反应条件
1: phenylmethyl (S)-1-(1,1-dimethylethoxycarbonyl)-5-oxopyrrolidine-2-carboxylate With hydrogen; palladium on activated charcoal in ethyl acetate 2: di-tert-butyl dicarbonate With 4-(N,N-dimethlyamino)pyridine; TEA in acetonitrile Further stages.;
参考文献
Tetrahedron, , vol. 60, # 45 p. 10277 - 10284
反应条件
1.1: 85 percent / TEA / acetone 2.1: 73 percent / DMAP / acetonitrile 3.1: H2 / Pd/C / ethyl acetate 3.2: 83 percent / DMAP; TEA / acetonitrile View Scheme
参考文献
Tetrahedron, , vol. 60, # 45 p. 10277 - 10284
反应条件
ruthenium(IV) oxide; sodium periodate in ethyl acetate 2 h; Ambient temperature;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 34, # 9 p. 3873 - 3878
反应条件
1: 61 percent / aq. HClO4 2: 91 percent / DMAP View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 11 p. 4164 - 4169
反应条件
1.1: 73 percent / DMAP / acetonitrile 2.1: H2 / Pd/C / ethyl acetate 2.2: 83 percent / DMAP; TEA / acetonitrile View Scheme
参考文献
Tetrahedron, , vol. 60, # 45 p. 10277 - 10284
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in acetonitrile Ambient temperature;
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 6 p. 507 - 514
反应条件
4-(N,N-dimethlyamino)pyridine in tert-butyl alcohol T=20°C; 12 h; Inert atmosphere;
参考文献
Tetrahedron, , vol. 69, # 33 p. 6821 - 6825
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane Ambient temperature;
参考文献
Tetrahedron, , vol. 45, # 23 p. 7459 - 7468