lt;(S)-2-(methoxymethyl)pyrolidinogt;cuprate in diethyl ether T=-25°C; asymmetric induction with other chiral heterocuprates, other solvents and at various temperature; Product distribution;
参考文献
Dieter,R.K.; Tokles,M.
Journal of the American Chemical Society, 1987 , vol. 109, p. 2040
1: methyllithium With copper (I) cyanide; lithium bromide in diethyl ether T=-78°C; 0.5 h; 2: With chloro-trimethyl-silane in diethyl ether 3: (+)-(2S)-N-[cyclohex-2-en-1-yliden]-2-(methoxymethyl)pyrrolidin-1-amine optical yield given as percent eeenantioselective reactionFurther stages;
参考文献
Sammet, Karsten; Gastl, Christoph; Baro, Angelika; Laschat, Sabine; Fischer, Peter; Fettig, Ina
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 13 p. 2281 - 2290
var. ratio and the order of addition of reaction partners; Product distribution;
参考文献
Koval'skaya, S. S.; Kozlov, N. G.; Knizhnikov, V. A.; Makhnach, S. A.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 11 p. 1818 - 1823
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 11 p. 2191 - 2197
(CH3)3CBr in not given addn. of MeLi to Fe-complex at -78°C (under N2), 7 h at -78°C, quenching with an excess of (CH3)3CBr;
参考文献
Danks, Timothy N.; Rakshit, Devajyoti; Thomas, Susan E.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2091 - 2094
