1: anhydrous L-lysine monohydrochloride With cupric(II) carbonate in water
T=90°C;
2: 2-methyl-acryloyl chloride With potassium hydroxide in water; acetone
T=3°C;
3: With 8-hydroxy-quinoline in chloroform; water
Reflux;
参考文献
Trombino, Sonia; Cassano, Roberta; Cilea, Alessia; Ferrarelli, Teresa; Muzzalupo, Rita; Picci, Nevio
International Journal of Pharmaceutics, 2011 , vol. 420, # 2 p. 290 - 296
Barros, M. Teresa; Mouquinho, Ana I.; Petrova, Krasimira T.; Saavedra, Mara D.; Sotomayor, Joao C.
Central European Journal of Chemistry, 2011 , vol. 9, # 4 p. 557 - 566
1: 2-(3,4-dihydroxyphenyl)ethylamine hydrochloride With Na2B4O7; sodium carbonate in water
pH=> 9.5; Inert atmosphere;
2: 2-methyl-acryloyl chloride With sodium carbonate in water
T=20°C; pH=Ca. 9.8; Inert atmosphereCooling with ice;
3: With hydrogenchloride in water
pH=1 - 2;
参考文献
Ham, Hyun Ok; Liu, Zhongqiang; Lau, K. H. Aaron; Lee, Haeshin; Messersmith, Phillip B.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 3 p. 732 - 736
