N-BOC-1,2丁二烯胺--庄合成路线 （共 4 条）
反应条件
formaldehyd; acetic acid; diisopropylamine; copper(I) bromide in hexane; water
参考文献
Merrell Pharmaceuticals, Inc.
Patent: US5719193 A1, 1998 ;
反应条件
diisopropylamine; copper(I) bromide in 1,4-dioxane
12 h; Heating;
参考文献
Casara, Patrick; Jund, Karin; Bey, Philippe
Tetrahedron Letters, 1984 , vol. 25, # 18 p. 1891 - 1894
反应条件
1: Et3N / CH2Cl2 / 2 h
2: diisopropylamine; CuBr / dioxane / 12 h / Heating
View Scheme
参考文献
Qiao, Chunhua; Jeon, Heung-Bae; Sayre, Lawrence M.
Journal of the American Chemical Society, 2004 , vol. 126, # 25 p. 8038 - 8045
反应条件
diisopropylamine; copper(I) bromide
2.) dioxane, reflux, 1 h; Multistep reaction;
参考文献
Bey, Philippe; Bolkenius, Frank N.; Seiler, Nikolaus; Casara, Patrick
Journal of Medicinal Chemistry, 1985 , vol. 28, # 1 p. 1 - 2
