2,5-二甲氧基苯甲醛合成路线 （共 179 条）
反应条件
hydrogenchloride; methyl iodide 1) ether, hexane, rt, 1 h; 2) ether, hexane, -65 deg C, rt, 1 h; 3) THF, reflux, 1.5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 61, # 14 p. 4812 - 4815
反应条件
hydrogenchloride; n-butyllithium 1) ether, hexane, rt, 1 h; 2) ether, hexane, -65 deg C, rt, 1 h; 3) THF, reflux, 1.5 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 61, # 14 p. 4812 - 4815
反应条件
aluminium trichloride Verseifen des gebildeten Esters, Kochen der 2.5-Dimethoxy-phenylglyoxylsaeure mit Anilin und Zerzetzen des so enstehenden <2.5-Dimethoxy-benzal>-anilins mit verd. Schwefelsaeure;
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 122, p. 1545
Bulletin de la Societe Chimique de France, , vol. <3>17, p. 947
参考文献
Chemische Berichte, , vol. 14, p. 1986
参考文献
Journal of the Chemical Society, , p. 2340
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 12 p. 4935 - 4941
反应条件
T=50°C; nachfolgend Hydrolyse des Reaktionsprodukts mit Salzsaeure;
参考文献
Journal of the Chemical Society, , p. 1482
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 291, p. 377,379-383
Archiv der Pharmazie (Weinheim, Germany), , vol. 291, p. 350
反应条件
1: 82 percent / NaH / dimethylsulfoxide; tetrahydrofuran / 1. 0 deg C, 2. room temp., 15 h. 2: 91 percent / H2 / 10percent Pd/C / ethanol / 0.33 h View Scheme
参考文献
Salley, John J.; Glennon, Richard A.
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 545 - 550
反应条件
1: 94 percent / hydroxylamine hydrochloride / ethanol; H2O / 2 h / 70 °C 2: N-chlorosuccinimide; pyridine / CHCl3 / 0.17 h / 25 °C View Scheme
参考文献
Zhu, Shirong; Shi, Shuhao; Gerritz, Samuel W.
Tetrahedron Letters, 2011 , vol. 52, # 31 p. 4001 - 4004
