1-苯基-1,3-丁二酮合成路线 （共 471 条）
反应条件
1: 80 percent / hydrochloric acid (conc.) / ethanol / 24 h / Heating
2: 61 percent / sodium hydroxide / H2O / 1 h
View Scheme
参考文献
Brown; Cowden; Lan; Mori
Australian Journal of Chemistry, 1984 , vol. 37, # 1 p. 155 - 163
反应条件
Zn(II)(acetylacetonate)2 in toluene
T=18 - 22°C; 20 h;
参考文献
Basato, M.; Corain, B.; Veronese, A. C.; D'Angeli, F.; Valle, G.; Zanotti, G.
Journal of Organic Chemistry, 1984 , vol. 49, # 24 p. 4696 - 4700
参考文献
Traube,W.; Sander
Justus Liebigs Annalen der Chemie, 1904 , vol. 332, p. 157
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane
T=25°C; 15 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Alvernhe, Gerard; Bensadat, Abdelkader; Ghobsi, Abdelkader; Laurent, Andre; Laurent, Eliane
Journal of Fluorine Chemistry, 1997 , vol. 81, # 2 p. 169 - 172
反应条件
acetic acid in ethanol
30 h; Heating / reflux;
参考文献
SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES
Patent: EP2039677 A1, 2009 ;
Location in patent: Page/Page column 9 ;
反应条件
acetic acid in ethanol
24 h; Heating / reflux;
参考文献
SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES
Patent: EP2039677 A1, 2009 ;
Location in patent: Page/Page column 10 ;
反应条件
formic acid in ethanol
20 h; Heating / reflux;
参考文献
SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES
Patent: EP2039677 A1, 2009 ;
Location in patent: Page/Page column 10 ;
反应条件
formic acid in ethanol
36 h; Heating / reflux;
参考文献
SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES
Patent: EP2039677 A1, 2009 ;
Location in patent: Page/Page column 10 ;
反应条件
nickel diacetate
T=60°C; 0.85 h; Neat (no solvent);
参考文献
Liu, Ju-Yan; Cao, Gai-E.; Xu, Wei; Cao, Jie; Wang, Wei-Lu
Applied Organometallic Chemistry, 2010 , vol. 24, # 10 p. 685 - 691
反应条件
1: glacial acetic acid
2: concentrated sulfuric acid
View Scheme
参考文献
Buelow; Issler
Chemische Berichte, 1903 , vol. 36, p. 2452
