4-(1-哌啶羰基)苯硼酸频哪醇酯合成路线 （共 4 条）
反应条件
benzotriazol-1-ol; triethylamine in N,N-dimethyl-formamide
T=20°C; 48 h; Inert atmosphere;
参考文献
De Simone, Rosa; Bruno, Ines; Riccio, Raffaele; Stadler, Katharina; Bauer, Julia; Schaible, Anja M.; Laufer, Stefan; Werz, Oliver
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 16 p. 5012 - 5016
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in 1,4-dioxane; dichloromethane
T=80°C; 12 h;
参考文献
Patel, Gautam; Karver, Caitlin E.; Behera, Ranjan; Guyett, Paul J.; Sullenberger, Catherine; Edwards, Peter; Roncal, Norma E.; Mensa-Wilmot, Kojo; Pollastri, Michael P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3820 - 3832
反应条件
1: ethyl acetate / 4 h / Inert atmosphere
2: benzotriazol-1-ol; triethylamine / N,N-dimethyl-formamide / 48 h / 20 °C / Inert atmosphere
View Scheme
参考文献
De Simone, Rosa; Bruno, Ines; Riccio, Raffaele; Stadler, Katharina; Bauer, Julia; Schaible, Anja M.; Laufer, Stefan; Werz, Oliver
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 16 p. 5012 - 5016
反应条件
1: ethyl acetate / 4 h / Inert atmosphere
2: benzotriazol-1-ol; triethylamine / N,N-dimethyl-formamide / 48 h / 20 °C / Inert atmosphere
View Scheme
参考文献
De Simone, Rosa; Bruno, Ines; Riccio, Raffaele; Stadler, Katharina; Bauer, Julia; Schaible, Anja M.; Laufer, Stefan; Werz, Oliver
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 16 p. 5012 - 5016
