1,2,3,4-四氢咔唑合成路线 （共 202 条）
反应条件
in neat (no solvent) T=180 - 185°C; 0.5 h;
参考文献
Rawal, Viresh H.; Cava, Michael P.
Tetrahedron Letters, 1985 , vol. 26, # 50 p. 6141 - 6142
反应条件
lithium aluminium tetrahydride in diethyl ether T=0°C; 2 h;
参考文献
Tetrahedron, , vol. 39, # 22 p. 3657 - 3668
反应条件
sulfuric acid in tetrahydrofuran T=20°C; 0.25 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 4, # 2 p. 302 - 313
反应条件
1: 88 percent / Cu powder / Pd(dba)2 / dimethylsulfoxide / 2 h / 70 °C 2: 60 percent / H2 / 10 percent Pd/C / methanol / 0.75 h / 735.51 Torr View Scheme
参考文献
Organic Letters, , vol. 5, # 14 p. 2497 - 2500
反应条件
acetic acid in sodium hydroxide; P2 O5; ethanol; water
反应条件
sulfuric acid in tetrahydrofuran T=20°C; 18 h;
参考文献
Linnepe, Petra; Schmidt, Axel M.; Eilbracht, Peter
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 2 p. 302 - 313
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II); diisobutylaluminium hydride in toluene 1 h; Ambient temperature;
参考文献
Taniguchi, Takahiko; Ogasawara, Kunio
Tetrahedron Letters, 1998 , vol. 39, # 26 p. 4679 - 4682
反应条件
toluene-4-sulfonic acid in ethanol Fischer cyclization; 1 h; Heating;
参考文献
Lim, Young-Kwan; Cho, Cheon-Gyu
Tetrahedron Letters, 2004 , vol. 45, # 9 p. 1857 - 1859
反应条件
caesium carbonate; bis(dibenzylideneacetone)-palladium(0) in toluene T=150°C; 24 h; Inert atmosphere;
参考文献
Tan, Yichen; Hartwig, John F.
Journal of the American Chemical Society, 2010 , vol. 132, # 11 p. 3676 - 3677
反应条件
potassium hydroxide in ethanol; water 2 h; Heating;
参考文献
Angewandte Chemie - International Edition, , vol. 44, # 3 p. 403 - 406
