2-溴-3-(溴甲基)吡啶合成路线 (共 6 条)
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane T=-10°C; 0.5 h;
参考文献
Maiti, Sarbendu; Achari, Basudeb; Mukhopadhyay, Ranjan; Banerjee, Asish Kr.
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 15 p. 1769 - 1773
反应条件
N-bromosuccinmide in tetrachloromethane 24 h; Heating;
参考文献
Rebek, Julius Jr.; Costello, Timothy; Wattley, Ruth
Journal of the American Chemical Society, 1985 , vol. 107, # 25 p. 7487 - 7493
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Rebek, Julius; Costello, Timothy
Heterocycles, 1984 , vol. 22, # 10 p. 2191 - 2194
反应条件
1: NaBH4 2: 86 percent / PBr3 / CH2Cl2 / 16 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 26 p. 6182 - 6189
反应条件
1: LDA 2: NaBH4 3: 86 percent / PBr3 / CH2Cl2 / 16 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 26 p. 6182 - 6189
反应条件
calcium carbonate in 1,4-dioxane; water
参考文献
Clive; Kang
Journal of Organic Chemistry, 2001 , vol. 66, # 18 p. 6083 - 6091
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
Yang, Shu-Wei; Ho, Ginny; Tulshian, Deen; Greenlee, William J.; Anthes, John; Fernandez, Xiomara; McLeod, Robbie L.; Hey, John A.; Xu, Xiaoying
Journal of Medicinal Chemistry, 2009 , vol. 52, # 17 p. 5323 - 5329