4-((5,5,8,8-四甲基-5,6,7,8-四氢萘-2-基)氨基甲酰基)苯甲酸甲酯合成路线 （共 9 条）
反应条件
pyridine in benzene Ambient temperature;
参考文献
Kagechika, Hiroyuki; Kawachi, Emiko; Hashimoto, Yuichi; Himi, Toshiyuki; Shudo, Koichi
Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2182 - 2192
反应条件
hydrogenchloride; phosphorus pentachloride; sodium hydrogencarbonate; 2,3-dimethyl aniline in methanol; dichloromethane; water
反应条件
1: conc. HCl, HCl gas / 0.25 h / 0 °C 2: 81.9 percent / AlCl3 / 24 h / Heating 3: 49.9 percent / HNO3, H2SO4 / 1 h / -10 °C 4: 48 percent / hydrogen / Pd/C / ethanol 5: 86.7 percent / pyridine / benzene / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 11 p. 2182 - 2192
反应条件
1: 81.9 percent / AlCl3 / 24 h / Heating 2: 49.9 percent / HNO3, H2SO4 / 1 h / -10 °C 3: 48 percent / hydrogen / Pd/C / ethanol 4: 86.7 percent / pyridine / benzene / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 11 p. 2182 - 2192
反应条件
1: 49.9 percent / HNO3, H2SO4 / 1 h / -10 °C 2: 48 percent / hydrogen / Pd/C / ethanol 3: 86.7 percent / pyridine / benzene / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 11 p. 2182 - 2192
反应条件
1: 48 percent / hydrogen / Pd/C / ethanol 2: 86.7 percent / pyridine / benzene / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 11 p. 2182 - 2192
反应条件
triethylamine in tetrahydrofuran T=-20°C; 1 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 61, # 8 p. 846 - 852
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 10 p. 4209 - 4212
反应条件
sodium hydroxide in ethanol Ambient temperature;
参考文献
Kagechika, Hiroyuki; Kawachi, Emiko; Hashimoto, Yuichi; Himi, Toshiyuki; Shudo, Koichi
Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2182 - 2192
