1: K2CO3 / dimethylformamide / 1.) 3 h, 2.) 60 - 65 deg C, 3 h, 3.) RT, overnight
2: 0.17 h / 245 - 250 °C
3: m-chloroperbenzoic acid / CH2Cl2 / 24 h / 10 - 20 °C
4: Kieselgel 60 / CH2Cl2 / 24 h / Ambient temperature
5: Jones' reagent / acetone / 48 h / Ambient temperature
6: thionyl chloride / benzene / 2.5 h / Heating
7: NH3 / dioxane / 2 h / Ambient temperature
8: P2O5 / toluene / 2 h / Heating
9: 1.) NaOCH3 / 1.) CH3OH, 2 h, 2.) CH3OH, 0 - 5 deg C, 0.25 h
View Scheme
参考文献
Chapleo, Christopher B.; Myers, Peter L.; Butler, Richard C. M.; Davis, John A.; Doxey, John C.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 570 - 576
Levas
Annales de Chimie (Cachan, France), 1948 , vol. <12> 3, p. 145,191
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1946 , vol. 223, p. 901,903 Anm.
