2,6-二叔丁基-4-巯基苯酚合成路线 (共 23 条)
反应条件
hydrogenchloride; zinc in ethanol; toluene Ambient temperature;
参考文献
Pastor, Stephen D.; Odorisio, Paul A.; Ravichandran, Ramanathan
Phosphorus and Sulfur and the Related Elements, 1987 , vol. 29, p. 67 - 72
反应条件
hydrogenchloride; zinc in methanol
参考文献
Justus Liebigs Annalen der Chemie, , vol. 645, p. 79 - 91
反应条件
1: With sulfur monochloride; iron in acetonitrile T=20°C; 18 h; 2: With hydrogenchloride; zinc in water; benzene T=60°C; 10 h;
参考文献
Tanaka, Hideo; Tokumaru, Yoshihisa; Fukui, Ken-Ichi; Kuroboshi, Manabu; Torii, Sigeru; Jutand, Anny; Amatore, Christian
Synthesis, 2009 , # 20 p. 3449 - 3459
参考文献
G. D. Searle and Co.; The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services
Patent: US5030642 A1, 1991 ;
参考文献
G. D. Searle and Co.
Patent: US5071876 A1, 1991 ;
反应条件
1: 73 percent / K2CO3 2: 30 percent / NaOH / ethanol View Scheme
参考文献
Portevin, Bernard; Lonchampt, Michel; Canet, Emmanuel; De Nanteuil, Guillaume
Journal of Medicinal Chemistry, 1997 , vol. 40, # 12 p. 1906 - 1918
反应条件
potassium hydroxide in ethanol T=65 - 70°C; 3 h; 1)5 deg C, 30 min 2)65 - 70 deg C, 3h;
参考文献
Kelarev, V. I.; Laawad Yakhya, F.; Karakhanov, R. A.; Lunin, A. F.; Malova, O. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 1 p. 89 - 94
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 1 p. 107 - 113
反应条件
in water; isopropyl alcohol byproducts: 3,3',5,5'-tetra-tert-butyldiphenoquinone; aq. Cu(II)-salt soln. addn. to org. compd. soln. (isopropanol), stirring with gentle heating to 70°C for 30-40-min, cooling; ppt. filtration off, washing (warm hexane), undissolved ppt. sepn., recrystn. (ethanol); elem. anal., IR and UV spectroscopy;
参考文献
Medzhidov, A. A.; Farzaliev, V. M.; Kasumov, V. T.; Allakhverdiev, M. A.; Mamedov, Ch. I.
Journal of General Chemistry USSR (English Translation), 1982 , vol. 52, p. 93 - 96
Zhurnal Obshchei Khimii, 1982 , vol. 52, p. 101 - 106
反应条件
copper diacetate in isopropyl alcohol T=70°C; 0.666667 h;
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 52, # 1 p. 101 - 106,93 - 96
反应条件
hydrogenchloride in methanol; water T=50 - 55°C; 5 h;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP1849768 A1, 2007 ;
Location in patent: Page/Page column 5 ;