isopropylmagnesium chloride in tetrahydrofuran
T=-10°C; 0.333333 h;
参考文献
Williams, J. Michael; Jobson, Ronald B.; Yasuda, Nobuyoshi; Marchesini, George; Dolling, Ulf-H.; Grabowski, Edward J. J.
Tetrahedron Letters, 1995 , vol. 36, # 31 p. 5461 - 5464
1: 3-methoxybromobenzene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.333333 h;
2: N-methoxy-N-methyl-2-phenylacetamide in tetrahydrofuran; hexane
Further stages.;
参考文献
Moreno, Isabel; Tellitu, Imanol; Dominguez, Esther; SanMartin, Raul
European Journal of Organic Chemistry, 2002 , # 13 p. 2126 - 2135
1: methanephosphonic acid dimethyl ester With n-butyllithium in tetrahydrofuran; hexane
T=0°C; Metallation; 0.333333 h;
2: N-methoxy-N-methyl-2-phenylacetamide in tetrahydrofuran; hexane
T=-78°C; Substitution; 0.5 h;
3: With hydrogenchloride in water
Hydrolysis;
