反应条件
1: N-(2,4-dinitrophenyl)benzeneamine With hydrogen; palladium 10 on activated carbon in ethyl acetate
52 h;
2: formic acid With hydrogenchloride in water
T=78 - 80°C; 22 h; Inert atmosphere;
3: With sodium hydroxide in water
T=20°C; pH=12;
参考文献
BURNHAM INSTITUTE FOR MEDICAL RESEARCH; MERCOLA, Mark; DAWSON, Marcia, I.; CASHMAN, John
Patent: WO2010/33643 A2, 2010 ;
Location in patent: Page/Page column 53; 54 ;
