2-苯基-1H-吲哚-5-甲腈合成路线 （共 19 条）
反应条件
potassium carbonate; L-proline; copper(I) bromide in dimethyl sulfoxide
T=100°C; 3 h; Inert atmosphere;
参考文献
Ponpandian, Thanasekaran; Muthusubramanian, Shanmugam
Tetrahedron Letters, 2012 , vol. 53, # 32 p. 4248 - 4252
反应条件
palladium diacetate; triphenylphosphine; silver carbonate in 1,4-dioxane
T=120°C; 24 h; Sealed tube;
参考文献
COUNCIL OF SCIENTIFIC and INDUSTRIAL RESEARCH; MHASKE, Santosh, Baburao; LANDE, Jyoti, Reveji
Patent: WO2013/117986 A1, 2013 ;
Location in patent: Page/Page column 19; 21; 24 ;
反应条件
indium tribromide in toluene
2 h; Heating;
参考文献
Sakai, Norio; Annaka, Kimiyoshi; Fujita, Akiko; Sato, Asuka; Konakahara, Takeo
Journal of Organic Chemistry, 2008 , vol. 73, # 11 p. 4160 - 4165
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in N,N-dimethyl acetamide
T=20°C; Sonogashira Cross-Coupling; 1 h;
2: With sodium hydroxide in N,N-dimethyl-aniline
T=140°C;
参考文献
Yu, Xufen; Park, Eun-Jung; Kondratyuk, Tamara P.; Pezzuto, John M.; Sun, Dianqing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 44 p. 8835 - 8847
反应条件
caesium carbonate in toluene
T=150°C; Sealed tube;
参考文献
Herrero, Maria Teresa; De Sarralde, Jokin Diaz; Sanmartin, Raul; Bravo, Laura; Dominguez, Esther
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 16 p. 3054 - 3064
反应条件
sulfuric acid; silver(I) acetate; palladium dichloride in N,N-dimethyl-formamide; acetonitrile
T=100°C; 0.666667 h; Sealed tubeMicrowave irradiation; regioselective reaction;
参考文献
Miao, Tao; Li, Pinhua; Wang, Guan-Wu; Wang, Lei
Chemistry - An Asian Journal, 2013 , vol. 8, # 12 p. 3185 - 3190
反应条件
dipotassium peroxodisulfate; sulfuric acid in methanol
T=20°C; 10 h;
参考文献
Zhang, Lei; Li, Pinhua; Liu, Can; Yang, Jin; Wang, Min; Wang, Lei
Catalysis Science and Technology, 2014 , vol. 4, # 7 p. 1979 - 1988
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
12 h; Heating;
参考文献
Yasuhara, Akito; Kanamori, Yuichi; Kaneko, Masashi; Numata, Atsushi; Kondo, Yoshinori; Sakamoto, Takao
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 4 p. 529 - 534
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride in tetrahydrofuran
4 h; Heating;
参考文献
Suzuki, Naoyuki; Yasaki, Sakura; Yasuhara, Akito; Sakamoto, Takao
Chemical and pharmaceutical bulletin, 2003 , vol. 51, # 10 p. 1170 - 1173
反应条件
[Rh(coe)2Cl]2; Cs(OPiv)2; tris(4-trifluoromethylphenyl)phosphine in 1,4-dioxane
T=120°C;
参考文献
Ambrus, Joseph I.; Kelso, Michael J.; Bremner, John B.; Ball, Anthony R.; Casadei, Gabriele; Lewis, Kim
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 15 p. 4294 - 4297
