potassium carbonate in acetone 6 h; Inert atmosphereReflux;

1.1: n-butyllithium / pentane; hexane / 0.25 h / -20 - -10 °C 1.2: trimethyl borate / pentane; hexane / 0.5 h / -30 - 0 °C 1.3: 87 percent / peracetic acid; acetic acid / pentane; hexane / -10 °C 2.1: aq. NaOH / 1.5 h / Heating View Scheme

1.1: 65 percent / Na2CO3 / N,N-dimethyl-acetamide / 3 h / Heating 2.1: KH2PO4; CF3CO3H / CH2Cl2 / 1 h / 0 °C 2.2: 98 percent / hydrochloric acid / methanol / 15 h 3.1: 93 percent / benzyltrimethylammonium tribromide; calcium carbonate / CH2Cl2; methanol / 20 °C 4.1: 96 percent / NaOH; tetrabutylammonium hydroxide / CH2Cl2; H2O / 5 h / 20 °C View Scheme

1.1: 65 percent / Na2CO3 / N,N-dimethyl-acetamide / 3 h / Heating 2.1: KH2PO4; CF3CO3H / CH2Cl2 / 1 h / 0 °C 2.2: 98 percent / hydrochloric acid / methanol / 15 h 3.1: 93 percent / benzyltrimethylammonium tribromide; calcium carbonate / CH2Cl2; methanol / 20 °C 4.1: 96 percent / NaOH; tetrabutylammonium hydroxide / CH2Cl2; H2O / 5 h / 20 °C View Scheme

1.1: KH2PO4; CF3CO3H / CH2Cl2 / 1 h / 0 °C 1.2: 98 percent / hydrochloric acid / methanol / 15 h 2.1: 93 percent / benzyltrimethylammonium tribromide; calcium carbonate / CH2Cl2; methanol / 20 °C 3.1: 96 percent / NaOH; tetrabutylammonium hydroxide / CH2Cl2; H2O / 5 h / 20 °C View Scheme

1: 93 percent / benzyltrimethylammonium tribromide; calcium carbonate / CH2Cl2; methanol / 20 °C 2: 96 percent / NaOH; tetrabutylammonium hydroxide / CH2Cl2; H2O / 5 h / 20 °C View Scheme

in sodium hydroxide 1.5 h; Heating;

hydrogen; palladium on activated charcoal in methanol T=25°C;