反应条件
lithium diisopropyl amide
1.) THF, hexane, -78 deg C, 45 min, 2.) THF, hexane, a) -78 deg C, 1 h, b) RT, 2 h; Yield given. Multistep reaction;
参考文献
SCHERING CORPORATION; BOGEN, Stephane, L.; MA, Yao; WANG, Yaolin; LAHUE, Brian Robert; NAIR, Latha, G.; SHIZUKA, Manami; VOSS, Matthew Ernst; KIROVA-SNOVER, Margarita; PAN, Weidong; TIAN, Yuan; KULKARNI, Bheemashankar, A.; GIBEAU, Craig, R.; LIU, Yuan; SCAPIN, Giovanna; RINDGEN, Diane; DOLL, Ronald, J.; GUZI, Timothy, J.; HICKLIN, Danny, J.; NOMEIR, Amin; SEIDEL-DUGAN, Cynthia; SHIPPS, Gerald, W., Jr.; MACCOSS, Malcolm
Patent: WO2011/46771 A1, 2011 ;
Location in patent: Page/Page column 178-179 ;
WO 2011/046771 A1
