chromium(VI) oxide in sulfuric acid; water; acetone T=-15°C; 0.5 h;

1: 61.7 percent / BuLi / tetrahydrofuran / 1.) 1 h, 0-10 deg C; 2.) -70 deg C 2: 92 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C View Scheme

1: 73 percent / CF3COOH / 120 h / Ambient temperature 2: 90 percent / LiBEt3H / tetrahydrofuran / -40 - 20 °C 3: 61.7 percent / BuLi / tetrahydrofuran / 1.) 1 h, 0-10 deg C; 2.) -70 deg C 4: 92 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C View Scheme

1: 95.8 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C 2: 73 percent / CF3COOH / 120 h / Ambient temperature 3: 90 percent / LiBEt3H / tetrahydrofuran / -40 - 20 °C 4: 61.7 percent / BuLi / tetrahydrofuran / 1.) 1 h, 0-10 deg C; 2.) -70 deg C 5: 92 percent / CrO3 / acetone; H2O; H2SO4 / 0.5 h / -15 °C View Scheme

暂无反应条件数据

1: 93 percent / BuLi / tetrahydrofuran / -70 °C 2: diisopropylethylamine / CH2Cl2 / 24 h / Ambient temperature 3: 93 percent / LiBEt3H / tetrahydrofuran / -40 - 20 °C View Scheme