2-羟基-4-甲基苯甲醛合成路线 （共 34 条）
反应条件
in neat (no solvent) T=79.9 - 179.9°C; effect of temperature; Equilibrium constant;
参考文献
Journal of applied chemistry of the USSR, , vol. 58, # 4 pt 1 p. 748 - 754
反应条件
in neat (no solvent) T=79.9 - 179.9°C; effect of temperature; Equilibrium constant;
参考文献
Journal of applied chemistry of the USSR, , vol. 58, # 4 pt 1 p. 748 - 754
参考文献
Industrial and Engineering Chemistry, , vol. 35, p. 264,270
Journal of the American Chemical Society, , vol. 67, p. 303,305
参考文献
US1972599 , ;
Chem.Abstr., , p. 6532
反应条件
1: With [bis(acetoxy)iodo]benzene; pyridine hydrogenfluoride in dichloromethane T=20°C; 0.25 h; 2: With trifluoroacetic acid in dichloromethane 0.166667 h;
参考文献
Gao, Zhanghua; Lim, Yee Hwee; Tredwell, Matthew; Li, Lei; Verhoog, Stefan; Hopkinson, Matthew; Kaluza, Wojciech; Collier, Thomas Lee; Passchier, Jan; Huiban, Mickael; Gouverneur, Veronique
Angewandte Chemie - International Edition, 2012 , vol. 51, # 27 p. 6733 - 6737
反应条件
1: With [Cu(I)(CH3CN)4]PF6; oxygen; triethylamine in dichloromethane T=-78°C; P=760.051 Torr; 8 h; Molecular sieve; 2: With toluene-4-sulfonic acid; 2-methylpropane-2-thiol in dichloromethane T=-78 - 23°C; 1 h;
参考文献
Esguerra, Kenneth Virgel N.; Fall, Yacoub; Petitjean, Laurene; Lumb, Jean-Philip
Journal of the American Chemical Society, 2014 , vol. 136, # 21 p. 7662 - 7668
反应条件
bromine in tetrachloromethane T=20°C; 2 h;
参考文献
PHENEX PHARMACEUTICALS AG; STEENECK, Christoph; KINZEL, Olaf; GEGE, Christian; KLEYMANN, Gerald; HOFFMANN, Thomas
Patent: WO2013/79223 A1, 2013 ;
Location in patent: Page/Page column 102 ;
参考文献
Dow Chem. Co.
Patent: US2221808 , 1935 ;
反应条件
in neat (no solvent) T=79.9 - 179.9°C; effect of temperature; Equilibrium constant;
参考文献
Nesterova; Verevkin; Malova; Pil'shchikov
Journal of applied chemistry of the USSR, 1985 , vol. 58, # 4 pt 1 p. 748 - 754
反应条件
1: 1.) H2; 2.) Na2Cr2O7, H2SO4 / 1.) PtO2 / 1.) acetic acid, 100 bar, RT; 2.) ether, water, 4h 2: 60 percent / p-toluolsulfonic acid / 4 h / solvent: pyrrolidine 3: 1.8 percent Chromat. / LiAlH4 / diethyl ether View Scheme
参考文献
Cherest, M.
Tetrahedron, 1980 , vol. 36, p. 1593 - 1598
