4-(2-吡啶基)-苯甲酸甲酯合成路线 （共 31 条）
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine in toluene
12 h; RefluxInert atmosphere;
参考文献
Xu, Jimin; Cheng, Guolin; Su, Deyong; Liu, Yantao; Wang, Xinyan; Hu, Yuefei
Chemistry - A European Journal, 2009 , vol. 15, # 47 p. 13105 - 13110
反应条件
1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / |Inert atmosphere
1.2: 2 h / -78 °C / |Inert atmosphere
1.3: 5 h / 20 °C / |Inert atmosphere
2.1: methanol / 15 h / 20 °C / |Inert atmosphere
3.1: PdCl2dcpp; copper(l) iodide; 2-methylamino-ethanol / N,N-dimethyl-formamide / 16 h / 100 °C / |Inert atmosphere
View Scheme
参考文献
Sakashita, Shohei; Takizawa, Miho; Sugai, Juugaku; Ito, Hajime; Yamamoto, Yasunori
Organic Letters, 2013 , vol. 15, # 17 p. 4308 - 4311
反应条件
FeCl3·6H2O; acetic acid; 1,4,7,10-tetraaza-cyclododecane
T=110°C; Suzuki-Miyaura reaction; 12 h; regioselective reaction;
参考文献
Wen, Jun; Qin, Song; Ma, Li-Fang; Dong, Liang; Zhang, Ji; Liu, Shan-Shan; Duan, Yi-Shu; Chen, Shan-Yong; Hu, Chang-Wei; Yu, Xiao-Qi
Organic Letters, 2010 , vol. 12, # 12 p. 2694 - 2697
反应条件
2,2'-azo-bisisobutyronitrile; tris-(trimethylsilyl)silane; acetic acid
T=80°C; 32 h;
参考文献
Nunez, Araceli; Sanchez, Aranzazu; Burgos, Carolina; Alvarez-Builla, Julio
Tetrahedron, 2004 , vol. 60, # 29 p. 6217 - 6224
反应条件
hydrogenchloride; methanol
参考文献
Butterworth et al.
Journal of the Chemical Society, 1940 , p. 355,357
反应条件
1: aqueous HCl / Diazotization
2: methanol; HCl
View Scheme
参考文献
Butterworth et al.
Journal of the Chemical Society, 1940 , p. 355,357
反应条件
1: aqueous HCl / Diazotization
2: aqueous NaOH
3: methanol; HCl
View Scheme
参考文献
Butterworth et al.
Journal of the Chemical Society, 1940 , p. 355,357
反应条件
1: aqueous NaOH
2: methanol; HCl
View Scheme
参考文献
Butterworth et al.
Journal of the Chemical Society, 1940 , p. 355,357
反应条件
1: aqueous HCl / Diazotization
2: methanol; HCl
View Scheme
参考文献
Butterworth et al.
Journal of the Chemical Society, 1940 , p. 355,357
反应条件
in dichloromethane
10 h; Ambient temperatureIrradiation; Yield given. Yields of byproduct given;
参考文献
Terashima, Masanao; Seki, Koh-ichi; Yoshida, Chihiro; Ohkura, Kazue; Kanaoka, Yuichi
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 3 p. 1009 - 1015
