1: With lithium hydroxide; water in tetrahydrofuran T=0 - 20°C; 4 h; 2: in water T=0°C; pH=2; Acidic aqueous solution;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '27521460', constants.ctx, '0')">Ru-MACHO</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587189', constants.ctx, '0')">hydrogen</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4153970', constants.ctx, '0')">sodium hydrogencarbonate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a> <br />T=25&deg;C;&nbsp;P=7500.75&nbsp;Torr;&nbsp;12&nbsp;h;&nbsp;&nbsp;GloveboxAutoclave;&nbsp;&nbsp;chemoselective reaction;&nbsp;<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a> <br />T=70 - 80&deg;C;&nbsp;4&nbsp;h;&nbsp;<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11323460', constants.ctx, '0')">ruthenium trichloride</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '1210618', constants.ctx, '0')">N,N-dioctyl-1-octylamine</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587189', constants.ctx, '0')">hydrogen</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />P=37503&nbsp;Torr;&nbsp;34&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 1) LDA / 1) THF, -60 deg C, 10 min<br />2: 91 percent / xylene / Heating<br />3: 1) ozone, 2) dimethyl sulfide / 1) -60 deg C, 2) room temperature<br /> <br /> &nbsp;