6-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮合成路线

参考文献

Universitat des Saarlandes
Patent: US2011/112067 A1, 2011 ;
Location in patent: Page/Page column 34; 35 ;
US 20110112067 A1

3279-90-16-溴-1,2,3,4-四氢-2-喹啉酮+

89878-14-8二乙基(3-吡啶基)硼烷

99471-41-76-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮

参考文献

Martinez; Walker; Hirschfeld; Bruno; Yang; Maloney
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 620 - 628

553-03-73,4-二氢-2(1H)-喹啉酮

99471-41-76-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮

参考文献

Martinez; Walker; Hirschfeld; Bruno; Yang; Maloney
Journal of Medicinal Chemistry, 1992 , vol. 35, # 4 p. 620 - 628

74497-02-2

99471-41-76-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮

参考文献

MERCK SHARP and DOHME CORP.; ElexoPharm GmbH; HOYT, Scott, B.; PETRILLI, Whitney Lane; LONDON, Clare; XIONG, Yusheng; TAYLOR, Jerry Andrew; ALI, Amjad; LO, Michael; HENDERSON, Timothy, J.; HU, Qingzhong; HARTMANN, Rolf; YIN, Lina; HEIM, Ralf; BEY, Emmanuel; SAXENA, Rohit; SAMANTA, Swapan Kumar; KULKARNI, Bheemashankar, A.
Patent: WO2012/148808 A1, 2012 ;
WO 2012/148808 A1

3460-04-63-氯-N-苯基丙酰胺

99471-41-76-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮

参考文献

MERCK SHARP and DOHME CORP.; ElexoPharm GmbH; HOYT, Scott, B.; PETRILLI, Whitney Lane; LONDON, Clare; XIONG, Yusheng; TAYLOR, Jerry Andrew; ALI, Amjad; LO, Michael; HENDERSON, Timothy, J.; HU, Qingzhong; HARTMANN, Rolf; YIN, Lina; HEIM, Ralf; BEY, Emmanuel; SAXENA, Rohit; SAMANTA, Swapan Kumar; KULKARNI, Bheemashankar, A.
Patent: WO2012/148808 A1, 2012 ;
WO 2012/148808 A1

626-55-13-溴吡啶+

3279-90-16-溴-1,2,3,4-四氢-2-喹啉酮

99471-41-76-(吡啶-3-基)-3,4-二氢喹啉-2(1H)-酮

参考文献

Alabaster; Bell; Campbell; Ellis; Henderson; Roberts; Ruddock; Samuels; Stefaniak
Journal of Medicinal Chemistry, 1988 , vol. 31, # 10 p. 2048 - 2056