lithium bromide

<b>Multi-step reaction with 4 steps<br /> </b>1.1: hydrogen bromide / water; toluene / 48 h / |Reflux; |Inert atmosphere<br />2.1: sodium iodide / acetone / |Reflux; |Inert atmosphere<br />3.1: copper(l) iodide / tetrahydrofuran / 0.25 h / -40 &deg;C / |Inert atmosphere<br />3.2: 3 h / -40 - 20 &deg;C / |Inert atmosphere<br />4.1: dmap; triethylamine / dichloromethane / 9 h / 0 - 20 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1.1: sodium iodide / acetone / |Reflux; |Inert atmosphere<br />2.1: copper(l) iodide / tetrahydrofuran / 0.25 h / -40 &deg;C / |Inert atmosphere<br />2.2: 3 h / -40 - 20 &deg;C / |Inert atmosphere<br />3.1: dmap; triethylamine / dichloromethane / 9 h / 0 - 20 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: copper(l) iodide / tetrahydrofuran / 0.25 h / -40 &deg;C / |Inert atmosphere<br />1.2: 3 h / -40 - 20 &deg;C / |Inert atmosphere<br />2.1: dmap; triethylamine / dichloromethane / 9 h / 0 - 20 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 0 - 20 &deg;C / |Inert atmosphere<br />2: Pd(P(t-Bu)2Me)2; potassium <i>tert</i>-butylate; N,N-dicyclohexylamine / 1,4-dioxane / 24 h / 20 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;