反应条件
3-(3,5-bis-trifluoromethyl-phenylamino)-4-{[(S)-(6-methoxy-quinolin-4-yl)-((R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methyl]-amino}-cyclobut-3-ene-1,2-dione in tert-butyl methyl ether
T=45°C; Michael condensation; 8 h; optical yield given as percent eeenantioselective reaction;
参考文献
Bae, Han Yong; Some, Surajit; Lee, Jae Heon; Kim, Ju-Young; Song, Myoung Jong; Lee, Sungyul; Zhang, Yong Jian; Song, Choong Eui
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 17 p. 3196 - 3202
