反应条件
1: 2-bromo-4-fluoro-1-methoxy-benzene; isopropylmagnesium chloride in tetrahydrofuran T=30°C; Grignard Reaction; 4.5 h; Inert atmosphere; 2: N,N-dimethyl-formamide in tetrahydrofuran T=45 - 55°C; Grignard Reaction; 1.5 h; Inert atmosphere; SolventTemperatureTime;
参考文献
Slattery, Catherine N.; Deasy, Rebecca E.; Maguire, Anita R.; Kopach, Michael E.; Singh, Utpal K.; Argentine, Mark D.; Trankle, William G.; Scherer, Roger Brian; Moynihan, Humphrey
Journal of Organic Chemistry, 2013 , vol. 78, # 12 p. 5955 - 5963