1: 1-(4-bromo-2-fluorobenzyl)pyrrolidine; isopropylmagnesium chloride in tetrahydrofuran T=5°C; 0.333333 h; 2: n-butyllithium in tetrahydrofuran; hexane T=5°C; 1 h;
参考文献
Hawkins, Joel M.; Dube, Pascal; Maloney, Mark T.; Wei, Lulin; Ewing, Marcus; Chesnut, Stephen M.; Denette, Joshua R.; Lillie, Brett M.; Vaidyanathan, Rajappa
Organic Process Research and Development, 2012 , vol. 16, # 8 p. 1393 - 1403
