2-甲基-2-环己烯-1-酮合成路线 （共 131 条）
反应条件
pyridine; dihydrogen peroxide in dichloromethane
T=0°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Girlanda-Junges, Celine; Keyling-Bilger, Florence; Schmitt, Gaby; Luu, Bang
Tetrahedron, 1998 , vol. 54, # 27 p. 7735 - 7748
反应条件
sodium hydroxide in methanol
T=0°C; graphite anode;
参考文献
Michaelis, Ralf; Mueller, Ulrich; Schaefer, Hans J.
Angewandte Chemie, 1987 , vol. 99, # 10 p. 1049 - 1050
反应条件
diallyl carbonate; palladium diacetate; 1,2-bis-(diphenylphosphino)ethane in acetonitrile
1 h; Heating; Yield given. Yields of byproduct given;
参考文献
Tsuji, Jiro; Minami, Ichiro; Shimizu, Isao
Tetrahedron Letters, 1983 , vol. 24, # 50 p. 5635 - 5638
反应条件
toluene-4-sulfonic acid; lithium diisopropyl amide
1.) THF, -23 deg C, 2 h, 2.) PhH, reflux, 15 min; Yield given. Multistep reaction;
参考文献
Wender, Paul A.; Erhardt, Jeanette M.; Letendre, Leo J.
Journal of the American Chemical Society, 1981 , vol. 103, # 8 p. 2114 - 2116
反应条件
1: POCl3 / trichloroethene / 1.) 10 deg C to r.t., 2.) 55 to 70 deg C, 3 h
2: NaBH4, 10percent aq. NaOH / methanol / Ambient temperature
3: chlorotrimethylsilane / 4 h / 140 °C
4: Na / 1.) toluene, 15 min, 2.) reflux, 2 min; reflux to r.t., 90 min
5: 1 M aq. HCl / tetrahydrofuran / 8 h / Ambient temperature
6: 82 percent / PPh3, CCl4 / 1 h / Heating
7: 71 percent / LiAlH4 / tetrahydrofuran / Ambient temperature
8: Ti(O-i-Pr)4, molecular sieves 4-Angstroem, O2, tetraphenylporphine / CH2Cl2 / 6 h / -10 - -5 °C / Irradiation
View Scheme
参考文献
Adam, Waldemar; Richter, Markus J.
Journal of Organic Chemistry, 1994 , vol. 59, # 12 p. 3341 - 3346
反应条件
1: chlorotrimethylsilane / 4 h / 140 °C
2: Na / 1.) toluene, 15 min, 2.) reflux, 2 min; reflux to r.t., 90 min
3: 1 M aq. HCl / tetrahydrofuran / 8 h / Ambient temperature
4: 82 percent / PPh3, CCl4 / 1 h / Heating
5: 71 percent / LiAlH4 / tetrahydrofuran / Ambient temperature
6: Ti(O-i-Pr)4, molecular sieves 4-Angstroem, O2, tetraphenylporphine / CH2Cl2 / 6 h / -10 - -5 °C / Irradiation
View Scheme
参考文献
Adam, Waldemar; Richter, Markus J.
Journal of Organic Chemistry, 1994 , vol. 59, # 12 p. 3341 - 3346
反应条件
1: 82 percent / PPh3, CCl4 / 1 h / Heating
2: 71 percent / LiAlH4 / tetrahydrofuran / Ambient temperature
3: Ti(O-i-Pr)4, molecular sieves 4-Angstroem, O2, tetraphenylporphine / CH2Cl2 / 6 h / -10 - -5 °C / Irradiation
View Scheme
参考文献
Adam, Waldemar; Richter, Markus J.
Journal of Organic Chemistry, 1994 , vol. 59, # 12 p. 3341 - 3346
反应条件
1: NaBH4, 10percent aq. NaOH / methanol / Ambient temperature
2: chlorotrimethylsilane / 4 h / 140 °C
3: Na / 1.) toluene, 15 min, 2.) reflux, 2 min; reflux to r.t., 90 min
4: 1 M aq. HCl / tetrahydrofuran / 8 h / Ambient temperature
5: 82 percent / PPh3, CCl4 / 1 h / Heating
6: 71 percent / LiAlH4 / tetrahydrofuran / Ambient temperature
7: Ti(O-i-Pr)4, molecular sieves 4-Angstroem, O2, tetraphenylporphine / CH2Cl2 / 6 h / -10 - -5 °C / Irradiation
View Scheme
参考文献
Adam, Waldemar; Richter, Markus J.
Journal of Organic Chemistry, 1994 , vol. 59, # 12 p. 3341 - 3346
反应条件
2: 1.) Br2, 2.) Bu4NF / 1.) CCl4, 0 deg C, 2.) THF, room temperature, 1 h
View Scheme
参考文献
Cuadrado, P.; Gonzalez, A.M.; Gonzalez, B.; Pulido, F.J.
Synthetic Communications, 1989 , vol. 19, # 1, 2 p. 275 - 284
反应条件
1: NEt3 / ZnCl2 / hydroquinone / benzene
2: 85 percent / CH2Cl2 / 25 °C
3: NaIO4 / methanol; H2O / 1 h / Ambient temperature
View Scheme
参考文献
Toshimitsu, Akio; Owada, Hiroto; Terao, Keiji; Uemura, Sakae; Okano, Masaya
Journal of Organic Chemistry, 1984 , vol. 49, # 20 p. 3796 - 3800
