1-(4-溴苯肼)-2-苯乙炔合成路线 （共 49 条）
反应条件
copper (II) acetate monohydrate; tert-butyl alcohol; (9,9-dimethyl-9H-xanthene-4,5-diyl)bis(bis(3,5-bis(trifluoromethyl)phenyl)phosphine) in tetrahydrofuran T=65°C; 20 h; Inert atmosphere; stereoselective reaction;
参考文献
Semba, Kazuhiko; Fujihara, Tetsuaki; Xu, Tinghua; Terao, Jun; Tsuji, Yasushi
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 8 p. 1542 - 1550
反应条件
1: With ethylmagnesium bromide; iron(II) chloride in diethyl ether T=20°C; 0.25 h; Inert atmosphere; 2: With hydrogenchloride; water in diethyl ether stereoselective reaction;
参考文献
Ilies, Laurean; Yoshida, Takumi; Nakamura, Eiichi
Journal of the American Chemical Society, 2012 , vol. 134, # 41 p. 16951 - 16954,4
反应条件
palladium dichloride in chlorobenzene 5 h; Reflux; Overall yield = 87 percent;
参考文献
Xie, Hou-Zhi; Gao, Qi; Liang, Ying; Wang, Heng-Shan; Pan, Ying-Ming
Green Chemistry, 2014 , vol. 16, # 4 p. 2132 - 2135
反应条件
n-butyllithium Multistep reaction;
参考文献
Tsuchihara, Kenji; Masuda, Toshio; Higashimura, Toshinobu
Journal of the American Chemical Society, 1991 , vol. 113, # 22 p. 8548 - 8549
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran Heating;
参考文献
Pena, Miguel A.; Perez Sestelo, Jose; Sarandeses, Luis A.
Synthesis, 2005 , # 3 art. no. Z14204SS, p. 485 - 492
反应条件
palladium dichloride in chlorobenzene 5 h; Reflux; Overall yield = 87 percent;
参考文献
Xie, Hou-Zhi; Gao, Qi; Liang, Ying; Wang, Heng-Shan; Pan, Ying-Ming
Green Chemistry, 2014 , vol. 16, # 4 p. 2132 - 2135
反应条件
oxygen; palladium diacetate; zinc(II) chloride T=100°C; P=5700.38 Torr; 24 h;
参考文献
Wang, Azhong; Jiang, Huanfeng
Journal of the American Chemical Society, 2008 , vol. 130, # 15 p. 5030 - 5031
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran Heating;
参考文献
Pena, Miguel A.; Perez Sestelo, Jose; Sarandeses, Luis A.
Synthesis, 2005 , # 3 art. no. Z14204SS, p. 485 - 492
反应条件
copper(l) iodide; potassium carbonate; triphenylphosphine in dimethyl sulfoxide
T=90°C; 24 h; Inert atmosphere;
参考文献
Li, Tingyi; Sun, Peng; Yang, Hailong; Zhu, Yan; Yan, Hong; Lu, Linhua; Mao, Jincheng
Tetrahedron, 2012 , vol. 68, # 32 p. 6413 - 6419
反应条件
copper(l) iodide; 8-hydroxy-quinoline; sodium salt of phosphorous acid in ethanol
T=80°C; Suzuki coupling; 24 h;
参考文献
Wang, Shihua; Wang, Min; Wang, Lei; Wang, Bo; Li, Pinhua; Yang, Jin
Tetrahedron, 2011 , vol. 67, # 26 p. 4800 - 4806
