136918-14-4合成路线 （共 708 条）
反应条件
pyridine; oxygen; copper diacetate in dichloromethane
168 h;
参考文献
Huegel, Helmut M.; Rix, Colin J.; Fleck, Karin
Synlett, 2006 , # 14 p. 2290 - 2292
反应条件
tri-tert-butyl phosphine; [bis(acetoxy)iodo]benzene; palladium diacetate
T=100°C; 33 h; Inert atmosphereGlovebox; Overall yield = 72 percent; Overall yield = 251 mg;
参考文献
Shrestha, Ruja; Mukherjee, Paramita; Tan, Yichen; Litman, Zachary C.; Hartwig, John F.
Journal of the American Chemical Society, 2013 , vol. 135, # 23 p. 8480 - 8483
反应条件
1: 39 percent / pyridine / butan-1-ol / 16 h / Heating
2: 87 percent / Dess-Martin periodinane / CH2Cl2; dimethylsulfoxide / 3 h / 60 °C
View Scheme
参考文献
Baxter, Ellen W.; Reitz, Allen B.
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 7 p. 763 - 768
反应条件
ethanol; N-benzyl-N,N,N-triethylammonium chloride; sodium
5 h; Heating;
参考文献
Komarova, L. I.; Pokrovskaya-Dukhnenko, E. M.; Zaiko, I. A.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 11 p. 2089 - 2092
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 11 p. 2327 - 2331
反应条件
di-isopropyl azodicarboxylate; thiamine diphosphate in tetrahydrofuran
Mitsunobu reaction;
参考文献
Wilkinson, Mark C.
Tetrahedron Letters, 2005 , vol. 46, # 28 p. 4773 - 4775
参考文献
Piutti
Gazzetta Chimica Italiana, 1883 , vol. 13, p. 334,335
Chemische Berichte, 1883 , vol. 16, p. 1320
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20 - 70°C;
参考文献
ATHERSYS, INC.
Patent: WO2006/34419 A2, 2006 ;
Location in patent: Page/Page column 73 ;
WO 2006/034419 A2
反应条件
1: t-BuOK / dimethylformamide / 1 h / Ambient temperature
2: NaBH4 / propan-2-ol; toluene; H2O / 4 h / 0 °C
View Scheme
参考文献
Fichert, Thomas; Massing, Ulrich
Tetrahedron Letters, 1998 , vol. 39, # 28 p. 5017 - 5018
反应条件
1: 1) chlorine, 2) N(Et)3 / 1) CH2Cl2, 0 deg C, 10 min, 2) CH2Cl2, r. t., 1 h
2: 76 percent / 3-chloroperbenzoic acid / CH2Cl2 / 0.5 h / 0 °C
View Scheme
参考文献
Bozkurt, Yasemin Soydas; Kutuk, Halil
Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 11 p. 2250 - 2257
反应条件
[bis(acetoxy)iodo]benzene in 1,2-dichloro-ethane
T=140°C; 4 h;
参考文献
Kim, Hyun Jin; Kim, Jiyu; Cho, Seung Hwan; Chang, Sukbok
Journal of the American Chemical Society, 2011 , vol. 133, # 41 p. 16382 - 16385
